, Volume 282, Issue 3, pp 235-239
Date: 11 May 2010

Polycystic ovarian syndrome and pregnancy outcome

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Abstract

Introduction

Polycystic ovarian syndrome (PCOS) is a common disease of the endocrine system among the women of reproductive age with an incidence ranging from 5 to 10%.

Method

This study is a mini-review of pregnancy and perinatal outcome in women with PCOS.

Results

The syndrome is associated with increased risk of pregnancy complications such as gestational diabetes, gestational hypertension, preeclampsia, and preterm labor, while no strong association was found with congenital anomalies or spontaneous miscarriages. Furthermore, women with PCOS seem to experience increased risk of cesarean delivery while their newborns face increased perinatal morbidity and mortality. Metformin use seems to reduce the risk of obstetrical complications; however, prospective studies are necessary on the field.

Conclusion

Further studies should be organised in order to evaluate the role of PCOS in pregnancy.