Combined positron emission tomography–computed tomography and tumor markers for detecting recurrent ovarian cancer
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
To evaluate the accuracy of integrated FDG-PET/CT and tumor markers for the depiction of recurrent ovarian carcinoma.
Patients with pathologically proven ovarian cancer, who underwent cytoreductive surgery and 3–6 cycles of adjuvant chemotherapy, were included in this study. They all underwent a thorough physical examination, tumor marker determination, and FDG-PET/CT imaging. The sensitivity, specificity, accuracy, and positive and negative predictive values for the tumor detection with PET/CT versus different tumor markers were performed in relation to the results at histological analysis after second-look surgery or clinical follow-up.
A total of 37 patients underwent FDG-PET/CT scans. Among them, 22 patients underwent exploratory laparotomy and 15 had diagnostic laparoscopy. Overall, 24 patients were documented to have ovarian cancer recurrence after second operation. FDG-PET/CT had sensitivity, specificity, accuracy, and positive and negative predictive values of 100, 85, 94, 92, and 100%, respectively.
Our study has shown that PET/CT is a sensitive tool to assist in the early identification and recurrent ovarian cancer, amenable to secondary cytoreduction.
- Combined positron emission tomography–computed tomography and tumor markers for detecting recurrent ovarian cancer
Archives of Gynecology and Obstetrics
Volume 283, Issue 2 , pp 335-341
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- Serum tumor marker
- Positron emission tomography–computed tomography
- Recurrent ovarian cancer
- Industry Sectors
- Author Affiliations
- 1. Department of Obstetrics and Gynecology, Shin-Kong Wu-Ho-Su Memorial Hospital, No 95, Wen-Chang Road, Shih-Lin District, Taipei, Taiwan
- 2. Medical College, Fu-Jen Catholic University, Taipei, Taiwan
- 3. College of Public Health, National Yang-Ming University, Taipei, Taiwan
- 4. Department of Radiology, Shin-Kong Wu-Ho-Su Memorial Hospital, Taipei, Taiwan