Archives of Gynecology and Obstetrics

, Volume 281, Issue 6, pp 1023–1028

Malignant mixed müllerian tumor of the fallopian tube: report of two cases and review of literature

  • Yang-Mei Shen
  • Yu-Ping Xie
  • Lian Xu
  • Kai-Xuan Yang
  • Na Yu
  • Yan Yu
  • Jing-Hua Wang
Gynecologic Oncology

DOI: 10.1007/s00404-009-1331-6

Cite this article as:
Shen, YM., Xie, YP., Xu, L. et al. Arch Gynecol Obstet (2010) 281: 1023. doi:10.1007/s00404-009-1331-6

Abstract

Purpose

Malignant mixed müllerian tumors (MMMT) of the female genital tract is rare and it is extremely rare in the fallopian tube, with fewer than 53 cases reported in the literature.

Methods

We had experienced two cases of MMMT of the fallopian tube. The clinical features, pathologic findings, diagnosis, therapy, and outcome were reviewed.

Results

The clinical features and diagnosis were similar to those of primary carcinoma of the fallopian tube. Histologically, the two patients had homologous and heterologous elements mixed müllerian tumors. Treatment has focused on surgery with postoperative chemotherapy. Prognosis is poor, with fewer than half of patients surviving 2 years.

Conclusions

MMMT of fallopian tube is an uncommon carcinoma in the female genital tract. Cervical cytology and endometrial curettage could raise the suspicion of a tubal malignancy, but diagnosis is not usually made until the time of surgery. The patient survival will improve after surgery and postoperative chemotherapy.

Keywords

Fallopian tube MMMT Immunohistochemistry 

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Yang-Mei Shen
    • 1
  • Yu-Ping Xie
    • 2
  • Lian Xu
    • 1
  • Kai-Xuan Yang
    • 1
  • Na Yu
    • 1
  • Yan Yu
    • 1
  • Jing-Hua Wang
    • 1
  1. 1.Department of Pathology, West China Second University HospitalSichuan UniversityChengduPeople’s Republic of China
  2. 2.Regenerative Medicine Research Center, West China HospitalSichuan UniversityChengduPeople’s Republic of China