Archives of Gynecology and Obstetrics

, Volume 283, Issue 1, pp 53–58

Effect of umbilical vein blood flow on perinatal outcome of fetuses with lean and/or hypo-coiled umbilical cord

  • Manal M. El behery
  • Amal A. Nouh
  • Amal M. Alanwar
  • Abdalla E. Diab
Materno-fetal Medicine

DOI: 10.1007/s00404-009-1272-0

Cite this article as:
El behery, M.M., Nouh, A.A., Alanwar, A.M. et al. Arch Gynecol Obstet (2011) 283: 53. doi:10.1007/s00404-009-1272-0

Abstract

Objective

To evaluate the effect of umbilical vein (UV) blood flow measured by color-directed pulsed-wave Doppler on perinatal outcome of fetuses with lean and/or hypocoiled umbilical cord after 24 weeks of gestation.

Methods

Two hundred and forty-four women with singleton fetus after 24 weeks of gestation were studied. Umbilical cord area, umbilical vessel cross-sectional area and antenatal umbilical coiling index (UCI) were calculated and compared with Doppler parameters including UV blood flow volume in ml/min/kg, UV peak systolic velocity in cm/s, and umbilical artery pulsatility index.

Results

Thirty-eight (15.5%) fetuses had lean umbilical cord (area < 10th percentile). A significant difference between fetuses with and those without lean cord was found in terms of: UCI (0.17 ± 0.06 vs. 0.35 ± 0.08, P < 0.001), cord cross-sectional area (89.6 ± 11.7 vs. 198.7 ± 33.7 mm2, P < 0.001), Wharton’s jelly amount (36.5 ± 11.2 vs. 125.2 ± 34.1 mm2, P < 0.001), UV blood flow (83.4 ± 15.8 vs. 131.0 ± 19.8 ml/min/kg, P < 0.001), and UV blood flow mean velocity (8.6 ± 3.7 vs. 12.1 ± 2.8 cm/s, P < 0.05). A significant positive correlation was found between antenatal UCI and UV blood flow (r = 0.73, P < 0.001).

Conclusion

Fetuses with lean and/or hypo-coiled umbilical cord showed a noticeable decrease in UV blood flow of sufficient magnitude that could affect fetal growth, and this could explain the higher prevalence of fetal intrapartum complications in growth-restricted fetuses.

Keywords

Lean umbilical cordUmbilical veinBlood flowPerinatal outcome

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Manal M. El behery
    • 1
  • Amal A. Nouh
    • 1
  • Amal M. Alanwar
    • 1
  • Abdalla E. Diab
    • 1
  1. 1.Obstetrics and Gynecology Department, Faculty of MedicineZagazig UniversityZagazigEgypt