Archives of Gynecology and Obstetrics

, 281:201

Brucellosis in pregnancy: a 6-year clinical analysis

  • Mertihan Kurdoglu
  • Ertan Adali
  • Zehra Kurdoglu
  • Mustafa Kasim Karahocagil
  • Ali Kolusari
  • Recep Yildizhan
  • Zehra Kucukaydin
  • Hanim Guler Sahin
  • Mansur Kamaci
  • Hayrettin Akdeniz
Original Article

DOI: 10.1007/s00404-009-1106-0

Cite this article as:
Kurdoglu, M., Adali, E., Kurdoglu, Z. et al. Arch Gynecol Obstet (2010) 281: 201. doi:10.1007/s00404-009-1106-0

Abstract

Aim

To review our experience with brucellosis in pregnancy and to characterize the risk factors, clinical presentations, the rates of possible perinatal complications, and the effect of hospitalization on pregnancy outcomes.

Methods

We reviewed the medical records of 21 pregnant women at a tertiary care hospital and 12 at a maternity hospital, who presented with acute, subacute, chronic, or relapsing brucellosis. Their risk factors and clinical presentations were defined. The reproductive outcomes of 29 cases were compared within themselves according to the hospitals they were managed and with the outcomes for all women followed in the maternity hospital for the period from January 2008 through December 2008.

Results

Consumption of unpasteurized dairy products had occurred in 92.3% of the cases. Spontaneous abortion, intrauterine fetal death, and preterm delivery rates were 24.14, 3.45, and 6.9%, respectively. Only spontaneous abortion rate substantially exceeded that among the general population of pregnant women in our maternity hospital (P < 0.05). Hospitalization did not affect pregnancy outcomes significantly (P > 0.05).

Conclusions

Brucellosis in pregnancy is associated with increased incidence of spontaneous abortion without an association with the magnitude of serum agglutination titer, the clinical type of brucellosis and hospitalization. In endemic areas with habitants of low socioeconomic class and low educational level, educating women of childbearing age about brucellosis may help to prevent the disease and its complications in pregnancy.

Keywords

BrucellaBrucellosis infectionPregnancyAbortionPreterm laborIntrauterine fetal demise

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Mertihan Kurdoglu
    • 1
    • 3
  • Ertan Adali
    • 1
  • Zehra Kurdoglu
    • 1
  • Mustafa Kasim Karahocagil
    • 2
  • Ali Kolusari
    • 1
  • Recep Yildizhan
    • 1
  • Zehra Kucukaydin
    • 1
  • Hanim Guler Sahin
    • 1
  • Mansur Kamaci
    • 1
  • Hayrettin Akdeniz
    • 2
  1. 1.Department of Obstetrics and GynecologyYuzuncu Yil University School of MedicineVanTurkey
  2. 2.Department of Clinical Microbiology and Infectious DiseasesYuzuncu Yil University School of MedicineVanTurkey
  3. 3.Yuzuncu Yil Universitesi Tip FakultesiVanTurkey