Archives of Gynecology and Obstetrics

, Volume 281, Issue 1, pp 145–150

Primary angiosarcoma of the ovary complicated by hemoperitoneum: a case report and review of the literature

Case Report

DOI: 10.1007/s00404-009-1092-2

Cite this article as:
Bradford, L., Swartz, K. & Rose, S. Arch Gynecol Obstet (2010) 281: 145. doi:10.1007/s00404-009-1092-2



Sarcomas of the female genital tract are very rare. A small subset of these, primary ovarian angiosarcoma, is even more rare, with only 26 cases reported in the literature. Most cases of advanced-stage disease are aggressive and demonstrate a poor response to both surgery and chemotherapy with an overall poor prognosis.


We present a case of a previously healthy 67-year-old woman who presented with abdominal pain and profound anemia. She underwent a full staging and optimal debulking that revealed Stage IIIC primary ovarian angiosarcoma. The patient died 3 weeks post-operatively secondary to hemorrhage from progressive, metastatic tumor sites prior to initiation of chemotherapy.


Primary ovarian angiosarcoma is extremely rare, often presenting in later stages with nonspecific symptoms. Immunohistochemical staining of pathological specimens can aid in the diagnosis. The optimal regimen for adjuvant chemotherapy is unknown, and the prognosis is very poor.


Ovarian cancerAngiosarcomaHemoperitoneum

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  1. 1.Department of Obstetrics and GynecologyUniversity of Wisconsin Hospital and ClinicsMadisonUSA
  2. 2.Department of PathologyMeriter HospitalMadisonUSA