Archives of Gynecology and Obstetrics

, Volume 280, Issue 2, pp 333–335

Peritoneal tuberculosis with elevated serum Ca-125 level mimicking advanced stage ovarian cancer: a case report

  • Orkun Tan
  • Edward Luchansky
  • Stephen Rosenman
  • Tarah Pua
  • Masoud Azodi
Letter to the Editor

DOI: 10.1007/s00404-009-0946-y

Cite this article as:
Tan, O., Luchansky, E., Rosenman, S. et al. Arch Gynecol Obstet (2009) 280: 333. doi:10.1007/s00404-009-0946-y

Abstract

Background

Tuberculosis is still a common problem in immigrant population with peritoneal tuberculosis as the most common presentation of extrapulmonary disease.

Case

A 36-year-old woman presented with abdominal distention, night sweats and weight loss. Physical examination and radiologic studies revealed ascites, omental caking and bilateral enlarged ovaries with an elevated serum Ca-125 of 353 U/mL. Acid-fast stain and culture were negative for Mycobacterium tuberculosis. Diagnostic laparoscopy and biopsy revealed multiple granulomas with epithelioid cells and caseification necrosis confirming tuberculosis. Treatment with anti-tuberculin drugs resulted in resolution of symptoms with a reduction in Ca-125 to normal.

Conclusion

Laparoscopic biopsy with frozen section evaluation would spare patients with peritoneal tuberculosis from unnecessary extensive surgery. Serum Ca-125 level may be useful in monitoring treatment response.

Keywords

Peritoneal tuberculosis Ovarian cancer Ca-125 

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Orkun Tan
    • 1
  • Edward Luchansky
    • 2
  • Stephen Rosenman
    • 2
  • Tarah Pua
    • 1
  • Masoud Azodi
    • 3
  1. 1.Department of Obstetrics and GynecologyNew York University School of MedicineNew YorkUSA
  2. 2.Department of Obstetrics and GynecologyBridgeport HospitalBridgeportUSA
  3. 3.Department of Obstetrics and GynecologyYale University School of MedicineNew HavenUSA

Personalised recommendations