Case Report

Archives of Gynecology and Obstetrics

, Volume 280, Issue 3, pp 485-487

First online:

Aggressive angiomyxoma of vulva recurring 8 years after initial diagnosis

  • Mehmet Coskun SalmanAffiliated withDepartment of Obstetrics and Gynecology, Faculty of Medicine, Hacettepe University Email author 
  • , Gamze Mocan KuzeyAffiliated withDepartment of Pathology, Faculty of Medicine, Hacettepe University
  • , Nasuh Utku DoganAffiliated withDepartment of Obstetrics and Gynecology, Faculty of Medicine, Hacettepe University
  • , Kunter YuceAffiliated withDepartment of Obstetrics and Gynecology, Faculty of Medicine, Hacettepe University

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Abstract

Background

Aggressive angiomyxoma is an uncommon soft tissue tumor which preferentially involves pelvic and vulvoperineal regions of young adult females. The typical characteristics include gelatinous appearance and locally infiltrative nature without evidence of nuclear atypia or mitosis. Treatment involves surgery, but local recurrence is high in spite of apparently complete surgical resection.

Case

A 28-year-old woman who had had a history of surgically excised aggressive angiomyxoma of vulva presented with a complaint of vulvar mass. The mass was removed and histopathologic examination revealed an aggressive angiomyxoma without necrosis, atypia, and mitosis.

Conclusion

Aggressive angiomyxoma should be kept in mind when an asymptomatic and slow-growing vulvar mass is detected in young females. The surgery should aim wide local excision and long-term follow-up is necessary due to high rate of local recurrence.

Keywords

Mesenchymal tumor Stroma Fibroblast Blood vessels Wide local excision Vulva