Quality of life of women with gynecologic cancer: associated factors

  • Ana Francisca Vaz
  • Aarão Mendes Pinto-Neto
  • Délio Marques Conde
  • Lúcia Costa-Paiva
  • Sirlei Siani Morais
  • Sérgio Barros Esteves
Original Article

DOI: 10.1007/s00404-007-0397-2

Cite this article as:
Vaz, A.F., Pinto-Neto, A.M., Conde, D.M. et al. Arch Gynecol Obstet (2007) 276: 583. doi:10.1007/s00404-007-0397-2

Abstract

Objective

To evaluate quality of life (QOL) and identify its associated factors in a cohort of women with gynecologic cancer.

Methods

A cross-sectional study was conducted, including 103 women with cervical or endometrial cancer, aged between 18 and 75 years who were receiving their entire treatment at the institution where the investigation was carried out. QOL was measured by the World Health Organization’s QOL instrument-abbreviated version (WHOQOL-BREF). Clinical and sociodemographic characteristics, in addition to prevalence of cancer-related symptoms prior to radiotherapy were investigated. Bivariate analysis was performed, applying the Mann–Whitney test. Multivariate analysis was used to identify factors associated with QOL.

Results

The mean age of the participants was 56.8 ± 11.6 years. The study included 67 (65%) women with cervical cancer and 36 (35%) women with endometrial cancer. Most participants were at an advanced stage (63.1%). The most common complaints were pain (49.5%) and vaginal bleeding (36.9%). The prevalence of anemia was 22.3%. On multivariate analysis, it was observed that anemia (P = 0.006) and nausea and/or vomiting (P = 0.010) determined impairment in physical domain. Pain negatively influenced physical domain (P = 0.001), overall QOL (P = 0.024), and general health (P = 0.013), while the history of surgery positively affected general health (P = 0.001).

Conclusion

Cancer-related symptoms were factors that most interfered with QOL in women with gynecologic cancer. Therefore, more attention should be focused on identifying these symptoms, adopting measures to minimize their repercussions on QOL.

Keywords

Cervical cancer Endometrial cancer WHOQOL-BREF questionnaire Anemia Pain 

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Ana Francisca Vaz
    • 1
  • Aarão Mendes Pinto-Neto
    • 1
  • Délio Marques Conde
    • 2
  • Lúcia Costa-Paiva
    • 1
  • Sirlei Siani Morais
    • 1
  • Sérgio Barros Esteves
    • 1
  1. 1.Department of Gynecology and ObstetricsUniversidade Estadual de Campinas, School of MedicineCampinasBrazil
  2. 2.Department of Gynecology and ObstetricsUniversidade Federal de Goiás, School of MedicineGoianiaBrazil

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