Archives of Gynecology and Obstetrics

, Volume 270, Issue 2, pp 116–118

Adenocarcinoma in situ coexisting with carcinoma in situ of the cervix during pregnancy

  • Miwa Nagaishi
  • Ritsuto Fujiwaki
  • Kohkichi Hata
  • Ken Makihara
  • Yoshio Yamane
  • Kohji Miyazaki
Case Report

DOI: 10.1007/s00404-002-0469-2

Cite this article as:
Nagaishi, M., Fujiwaki, R., Hata, K. et al. Arch Gynecol Obstet (2004) 270: 116. doi:10.1007/s00404-002-0469-2

Abstract

Case report

We report a pregnant patient with adenocarcinoma in situ (AIS) coexisting with carcinoma in situ (CIS) of the cervix diagnosed by conization at 16 weeks' gestation. Apoptotic activity was higher in the CIS lesion than in the AIS lesion in the cone biopsy specimen. Postpartum evaluation confirmed the disappearance of CIS lesion with positive cone margins, however, multifocal AIS with negative cone margins was found.

Conclusion

Clinical course and biological features of AIS associated with pregnancy may be different from those of CIS.

Keywords

Adenocarcinoma in situCarcinoma in situCervixPregnancyApoptosis

Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • Miwa Nagaishi
    • 1
  • Ritsuto Fujiwaki
    • 1
  • Kohkichi Hata
    • 1
  • Ken Makihara
    • 2
  • Yoshio Yamane
    • 2
  • Kohji Miyazaki
    • 1
  1. 1.Department of Obstetrics and GynecologyShimane Medical UniversityIzumoJapan
  2. 2.Department of Obstetrics and GynecologyGohtsu Saiseikai General HospitalGohtsuJapan