Archives of Dermatological Research

, Volume 306, Issue 3, pp 269–277

Clinical practice guidelines for treatment of acne vulgaris: a critical appraisal using the AGREE II instrument

  • Gloria Sanclemente
  • Jorge-Luis Acosta
  • Maria-Eulalia Tamayo
  • Xavier Bonfill
  • Pablo Alonso-Coello
Original Paper

DOI: 10.1007/s00403-013-1394-x

Cite this article as:
Sanclemente, G., Acosta, JL., Tamayo, ME. et al. Arch Dermatol Res (2014) 306: 269. doi:10.1007/s00403-013-1394-x

Abstract

A significant number of clinical practice guidelines (CPGs) about the treatment of acne vulgaris in adolescents and adults have been published worldwide. However, little is known about the quality of CPGs in this field. The aim of this study was to appraise the methodological quality of published acne vulgaris CPGs. We performed a systematic review of published CPGs on acne vulgaris therapy from July 2002 to July 2012. Three reviewers independently assessed each CPG using the AGREE II instrument. A standardized score was calculated for each of the six domains. Our search strategy identified 103 citations but just six met our inclusion criteria. Agreement among reviewers was very good: 0.981. The domains that scored better were: “scope and purpose” and “clarity and presentation”. Those that scored worse were “stakeholder involvement”, “rigor of development”, and “applicability”. The European and the Malaysian CPGs were the only recommended with no further modifications. In addition, the Mexican, Colombian and the United States guidelines were recommended with provisos, with lower scores regarding stakeholder involvement, rigor of development and applicability. Only two guidelines clearly reported outcome measures for evaluating efficacy or included quality of life outcomes. CPGs varied regarding the consideration of light/laser therapy or consideration of complementary/alternative medicines. None of them included cost considerations of drugs such as systemic isotretinoin. In conclusion, published acne vulgaris CPGs for acne therapy vary in quality with a clear need to improve their methodological rigor. This could be achieved with the adherence to current CPGs development standards.

Keywords

Acne vulgarisCritical appraisalClinical practice guidelinesAGREE II

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Gloria Sanclemente
    • 1
    • 5
  • Jorge-Luis Acosta
    • 2
  • Maria-Eulalia Tamayo
    • 3
  • Xavier Bonfill
    • 4
  • Pablo Alonso-Coello
    • 4
  1. 1.Group of Investigative Dermatology (GRID), School of MedicineUniversity of AntioquiaMedellínColombia
  2. 2.Public Health DepartmentUniversidad del NorteBarranquillaColombia
  3. 3.Pediatrics Department, School of MedicineUniversity of AntioquiaMedellínColombia
  4. 4.Iberoamerican Cochrane Center, IIB- Sant Pau, CIBERESP, Universitat Autònoma de BarcelonaBarcelonaSpain
  5. 5.PhD Program in Salud Pública y Metodología de la Investigación Biomédica of the Departament de Pediatria, d’Obstetrícia i Ginecologia i de Medicina PreventivaUniversitat Autònoma de BarcelonaBarcelonaSpain