Archives of Dermatological Research

, Volume 305, Issue 2, pp 91–98

Recommendations for detection of individual risk for comorbidities in patients with psoriasis

Authors

    • Department of Dermatology and VenereologyMartin-Luther-University Halle-Wittenberg
  • Gabriele Fiedler
    • Dermatological practice
  • Sascha Gerdes
    • Department of DermatologyAllergology and Venereology (Psoriasis-Centre) of University Medical Centre Schleswig-Holstein
  • Alexander Nast
    • Division of Evidence Based Medicine, University Clinic and Policlinic of Dermatology, Allergology and VenereologyCharité, University Medicine Berlin
  • Sandra Philipp
    • University Clinic and Policlinic of Dermatology, Allergology and VenereologyCharité, University Medicine Berlin
  • Marc A. Radtke
    • Institute for Health Services Research in Dermatology and NursingUniversity Medical Centre Hamburg-Eppendorf
  • Diamant Thaçi
    • Department of Dermatology, Venereology and AllergologyJ.W. Goethe University Hospital and Faculty of Medicine Frankfurt am Main
  • Wolfgang Koenig
    • Department of Internal Medicine II—Cardiology, Centre for Internal MedicineUniversity of Ulm
  • Andreas F. H. Pfeiffer
    • Endocrinology, Diabetes and Nutrition MedicineCharité, University Medicine Berlin
  • Martin Härter
    • Department of Medical Psychology, Centre for Psychosocial MedicineUniversity Medical Centre Hamburg-Eppendorf
  • Michael P. Schön
    • Department of Dermatology, Venereology and AllergologyUniversity Medical Centre Göttingen
Mini Review

DOI: 10.1007/s00403-013-1318-9

Cite this article as:
Wohlrab, J., Fiedler, G., Gerdes, S. et al. Arch Dermatol Res (2013) 305: 91. doi:10.1007/s00403-013-1318-9

Abstract

Since the pathogenesis of psoriasis vulgaris is now understood as a T cell mediated systemic auto-immune disease, the awareness for the potential systemic implications of the chronic active inflammation has grown. By evaluation of patient registries and study data, several complexes of comorbidities could be identified in recent years, albeit not all of them being clinically relevant. Comorbidity in this context will be defined as two or more diagnostically distinguished medical conditions existing simultaneously, but without a causal link. Nevertheless, there is some strong indication for pathogenetic link between some specified comorbidities and psoriasis at molecular and immunological level. The need for an interdisciplinary assessment of the potential interrelation is obvious. In order to detect the individual risk for comorbidities in patients with moderate to severe psoriasis and to recommend the course of action, a checklist has been developed at an interdisciplinary level that is reduced to the quintessential points for the use in daily practice.

Keywords

PsoriasisComorbidities

Copyright information

© Springer-Verlag Berlin Heidelberg 2013