Archives of Dermatological Research

, Volume 299, Issue 10, pp 499–505

Effect of oral intake of choline-stabilized orthosilicic acid on hair tensile strength and morphology in women with fine hair

Authors

  • R. R. Wickett
    • College of PharmacyUniversity of Cincinnati
  • E. Kossmann
    • Practice for Dermatology and Cosmetic Medicine
  • A. Barel
    • Faculty of Physical Education and PhysiotherapyVrije Universiteit Brussel
  • N. Demeester
    • Faculty of Pharmaceutical, Biomedical and Veterinary SciencesUniversity of Antwerp
  • P. Clarys
    • Faculty of Physical Education and PhysiotherapyVrije Universiteit Brussel
  • D. Vanden Berghe
    • Faculty of Pharmaceutical, Biomedical and Veterinary SciencesUniversity of Antwerp
    • Faculty of Pharmaceutical, Biomedical and Veterinary SciencesUniversity of Antwerp
Original Paper

DOI: 10.1007/s00403-007-0796-z

Cite this article as:
Wickett, R.R., Kossmann, E., Barel, A. et al. Arch Dermatol Res (2007) 299: 499. doi:10.1007/s00403-007-0796-z

Abstract

The appearance of hair plays an important role in people’s overall physical appearance and self-perception. Silicon (Si) has been suggested to have a role in the formation of connective tissue and is present at 1–10 ppm in hair. Choline-stabilized orthosilicic acid (“ch-OSA”) is a bioavailable form of silicon which was found to improve skin microrelief and skin mechanical properties in women with photoaged skin. The effect of ch-OSA on hair was investigated in a randomized, double blind, placebo-controlled study. Forty-eight women with fine hair were given 10 mg Si/day in the form of ch-OSA beadlets (n = 24) or a placebo (n = 24), orally for 9 months. Hair morphology and tensile properties were evaluated before and after treatment. Urinary silicon concentration increased significantly in the ch-OSA supplemented group but not in the placebo group. The elastic gradient decreased in both groups but the change was significantly smaller in the ch-OSA group (−4.52%) compared to placebo group (−11.9%). Break load changed significantly in the placebo group (−10.8%) but not in the ch-OSA supplemented group (−2.20%). Break stress and elastic modulus decreased in both groups but the change was smaller in the ch-OSA group. The cross sectional area increased significantly after 9 months compared to baseline in ch-OSA supplemented subjects but not in the placebo group. The change in urinary silicon excretion was significantly correlated with the change in cross sectional area. Oral intake of ch-OSA had a positive effect on tensile strength including elasticity and break load and resulted in thicker hair.

Keywords

HairTensile strengthCholine-stabilized orthosilicic acidElasticityBreak load

Copyright information

© Springer-Verlag 2007