Archives of Orthopaedic and Trauma Surgery

, Volume 121, Issue 9, pp 531–535

Risk factors for heterotopic ossification in total hip arthroplasty

  • S. Eggli
  • A. Woo
Original Article

DOI: 10.1007/s004020100287

Cite this article as:
Eggli, S. & Woo, A. Arch Orth Traum Surg (2001) 121: 531. doi:10.1007/s004020100287


This study prospectively evaluated 928 patients with 1318 primary total hip replacements for heterotopic ossification (HO). The mean clinical and radiological follow-up was 2.5 years (range 1.5–3.6 years). HO was noted in 44.6% of all total hips replaced. It was graded as mild (Brooker 1) in 29.2%, moderate (Brooker 2) in 10.5%, and severe (Brooker 3 and 4) in 4.2%. The following factors showed a significantly increased risk of HO: hypertrophic osteoarthritis, HO after contralateral total hip replacement, trochanteric osteotomy, lateral or anterolateral approach, previous hip surgery, subtrochanteric femoral osteotomy, and male gender (p < 0.05 in chi-square analysis of independence and multivariable analysis). Patients with rheumatoid arthritis showed less HO. A combination of any of these factors resulted in a significant increase in the risk of developing HO.

Keywords Hip prosthesisHeterotopic ossificationOsteoarthritisHip surgeryPostoperative complications

Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • S. Eggli
    • 1
  • A. Woo
    • 1
  1. 1.Department of Orthopaedic Surgery, University of Berne, Inselspital, 3010 Berne, Switzerland e-mail:, Tel.: +41-31-6322320, Fax: +41-31-6323700CH
  2. 2.Maurice E. Müller Foundation, Murtenstrasse 35, 3007 Berne, SwitzerlandCH