Acta Neuropathologica

, Volume 94, Issue 2, pp 187–191

Pseudopapillary neurocytoma of temporal lobe with glial differentiation

  • Duck Hwan Kim
  • Y.-L. Suh
Case report

DOI: 10.1007/s004010050692

Cite this article as:
Kim, D. & Suh, Y. Acta Neuropathol (1997) 94: 187. doi:10.1007/s004010050692


We present a case of cerebral neurocytoma with unusual pseudopapillary pattern, which was a predominant feature in the tumor and was characterized histologically by hyalinized vascular cores surrounded by a single or multilayered small round cells. Vascular hyalinization was also evident in the linear arborizing capillary networks in the cellular mass of the tumor. Immunohistochemically, the tumor cells were strongly positive for synaptophysin and neuron-specific enolase except some cells lining the pseudopapillae, which showed immunoreactivity for glial fibrillary acidic protein, vimentin and S-100 protein. Ultrastructural examination revealed neuritic process of the tumor cells with occasional synaptic structures and neurosecretory granules. This report suggests that neurocytoma should be included in the differential diagnosis of papillary tumors in the central nervous system.

Key words NeurocytomaPseudopapillary patternSynaptophysinGlial fibrillary acidic proteinDifferential diagnosis

Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • Duck Hwan Kim
    • 1
  • Y.-L. Suh
    • 1
  1. 1.Department of Diagnostic Pathology, Samsung Seoul Hospital, 50 ILwon-Dong, Kangnam-Ku, Seoul 135-710, Korea Tel.: 82-2-3410-2800; Fax: 82-2-3410-0025; e-mail: