Colloid and Polymer Science

, Volume 286, Issue 10, pp 1165–1171

Swelling behaviors of thermoresponsive hydrogels cross-linked with acryloyloxyethylaminopolysuccinimide

  • Yue-qin Yu
  • Yang Xu
  • Hansheng Ning
  • Shu-sheng Zhang
Original Contribution

DOI: 10.1007/s00396-008-1878-y

Cite this article as:
Yu, Y., Xu, Y., Ning, H. et al. Colloid Polym Sci (2008) 286: 1165. doi:10.1007/s00396-008-1878-y

Abstract

Based on a biodegradable cross-linker, acryloyloxyethylaminopolysuccinimide (AEA-PSI), a series of looser cross-linked poly(N-isopropylacrylamide-co-acrylic acid) [P(NIPAAm-co-AAc)] hydrogels were prepared, and their water content, swelling/deswelling kinetics, and the morphology of the gels were investigated. The swelling behaviors of AEA-PSI-cross-linked P(NIPAAm/AAc) hydrogels were investigated in Dulbecco’s phosphate-buffered saline (pH = 7.4), in the distilled water, and in the simulated gastric fluids (pH = 1.2), respectively. The water contents of the hydrogels were controlled by the monomer molar ratio of NIPAAm/AAc, swelling media, and the temperature. In the swelling kinetics, all the dried hydrogels exhibited fast swelling behavior, and the swelling ratios were influenced significantly by the amounts of AEA-PSI and AAc content. The deswelling kinetics of the hydrogel were independent of the content of AAc and cross-linker. Lastly, the morphology of the hydrogels was estimated by the field scan electron microscopy.

Keywords

Thermoresponsive hydrogelWater contentSwelling kineticsDeswelling kineticsMorphology

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Yue-qin Yu
    • 1
  • Yang Xu
    • 1
  • Hansheng Ning
    • 1
  • Shu-sheng Zhang
    • 1
  1. 1.Key laboratory of Eco-chemical Engineering, College of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdaoPeople’s Republic of China