European Journal of Nutrition

, Volume 51, Issue 7, pp 807–815

Moderate physical training attenuates muscle-specific effects on fibre type composition in adult rats submitted to a perinatal maternal low-protein diet

  • Carol Góis Leandro
  • Wellington da Silva Ribeiro
  • José Antônio dos Santos
  • Adriano Bento-Santos
  • Carlos Henrique Lima-Coelho
  • Filippe Falcão-Tebas
  • Cláudia Jacques Lagranha
  • Sandra Lopes-de-Souza
  • Raul Manhães-de-Castro
  • Ana Elisa Toscano
Original Contribution

DOI: 10.1007/s00394-011-0259-3

Cite this article as:
Leandro, C.G., da Silva Ribeiro, W., dos Santos, J.A. et al. Eur J Nutr (2012) 51: 807. doi:10.1007/s00394-011-0259-3

Abstract

Aim

To verify whether moderate physical training affects the muscle fibre composition of adult rats subjected to a low protein diet during the perinatal period.

Methods

Male Wistar rats were divided into two groups according to their mother’s diet during gestation and lactation: control (17% casein, C) and low-protein (8% casein, LP). On postnatal day 60, half of each group was submitted to moderate physical training (8 weeks, 5 days/week−1, 60 min/day−1, at 70% of VO2max, T) or not. After the physical training period, soleus and extensor digitorum longus (EDL) muscles were removed. Myofibrillar ATPase staining was used to classify muscle fibres as type I, IIa, IIb, and intermediate.

Results

In the EDL muscle, LP rats showed no changes in the fibre type proportion. Both the C + T and LP + T groups showed a higher percentage of fibres of type IIa, and a lower proportion of fibres of type IIb. In the soleus muscle, LP animals showed a reduction in the proportion of fibre types I and intermediate. C + T rats showed an increase in the fibre type I and IIa. In the LP + T rats, the proportions of the fibre types remained similar to control rats.

Conclusions

Moderate physical training acts as a positive environmental stimulus that reverts the effects of a perinatal low-protein diet on the proportion of fibre types in skeletal muscle.

Keywords

Perinatal undernutritionPhysical exerciseProgrammingMuscle type fibreRats

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Carol Góis Leandro
    • 1
  • Wellington da Silva Ribeiro
    • 2
  • José Antônio dos Santos
    • 3
  • Adriano Bento-Santos
    • 3
  • Carlos Henrique Lima-Coelho
    • 4
  • Filippe Falcão-Tebas
    • 1
  • Cláudia Jacques Lagranha
    • 1
  • Sandra Lopes-de-Souza
    • 2
  • Raul Manhães-de-Castro
    • 4
  • Ana Elisa Toscano
    • 1
  1. 1.Department of Physical Education and Sport ScienceNúcleo de Educação Física e Ciências do Esporte, Centro Acadêmico de Vitória CAV, Federal University of PernambucoRecifeBrazil
  2. 2.Department of Anatomy and MorphologyFederal University of PernambucoRecifeBrazil
  3. 3.Department of Neuropsychiatry and Behavioral ScienceFederal University of PernambucoRecifeBrazil
  4. 4.Department of NutritionFederal University of PernambucoRecifeBrazil