European Journal of Nutrition

, Volume 48, Issue 3, pp 129–136

Serum nutrients and habitual dietary intake in colectomized FAP patients in Norway

  • Kari Almendingen
  • Olau Fausa
  • Arne Tore Høstmark
  • Jorunn Bratlie
  • Lars Mørkerid
  • Lars Aabakken
  • Morten Harald Vatn
ORIGINAL CONTRIBUTION

DOI: 10.1007/s00394-008-0772-1

Cite this article as:
Almendingen, K., Fausa, O., Høstmark, A.T. et al. Eur J Nutr (2009) 48: 129. doi:10.1007/s00394-008-0772-1

Abstract

Background

Patients with familial adenomatous polyposis (FAP) are colectomized in young age in order to avoid development of colorectal cancer. Because colectomy radically changes gastrointestinal physiology, and food avoidance may be present, colectomized patients may be at risk for nutritional deficiency.

Aim of the study

to evaluate: (1) serum biochemical levels as compared to reference; (2) dietary intake as compared to the recommendations.

Methods

Blood samples, interviews and food frequency questionnaire were collected from 38 colectomized FAP patients with duodenal adenomas (mean age 40 years, range: 24–70). They were recruited from the Norwegian database on FAP.

Results

Serum albumin was significantly higher (P ≤ 0.0001), and Mg (P = 0.02), ferritin (P ≤ 0.001), and cholesterol (P = 0.03) significantly lower, than reference levels. Compared to recommendations, a low intake was seen for folate and fiber (<50%), iron, thiamin, riboflavin (<25%), and omega-3 fatty acids (8%). Sugar intake exceeded the recommendation, mainly due to a high intake of soft drinks. Food avoidance was reported by 53%.

Conclusions

We would suggest that the nutrient intake among FAP patients should at least meet the recommendations for healthy subjects. Their risk of metachronous cancers should also cause special attention to dietary factors that may prevent nutritional deficiency and carcinogenesis.

Keywords

familial adenomatous polyposisileostomycolectomydietnutritional status

Copyright information

© Steinkopff Verlag Darmstadt 2009

Authors and Affiliations

  • Kari Almendingen
    • 1
    • 2
  • Olau Fausa
    • 2
  • Arne Tore Høstmark
    • 3
  • Jorunn Bratlie
    • 2
  • Lars Mørkerid
    • 4
  • Lars Aabakken
    • 2
  • Morten Harald Vatn
    • 2
    • 5
  1. 1.Unit of Clinical Research, Research CenterAkershus University HospitalLørenskogNorway
  2. 2.Dept. of MedicineRikshospitalet University HospitalOsloNorway
  3. 3.Institute of General Practice and Community MedicineUniversity of OsloOsloNorway
  4. 4.Medical Center, Institute of Clinical BiochemistryUniversity of OsloOsloNorway
  5. 5.EpiGen, Faculty Division AkershusUniversity Hospital, University of OsloOsloNorway