Clinical Research in Cardiology

, Volume 103, Issue 12, pp 955–967

Cardiovascular sequelae of radiation therapy

Authors

  • Francesco Santoro
    • Cardiology DepartmentUniversity of Foggia
  • Nicola Tarantino
    • Cardiology DepartmentUniversity of Foggia
  • Pier Luigi Pellegrino
    • Cardiology DepartmentUniversity of Foggia
  • Marica Caivano
    • Cardiology DepartmentUniversity of Foggia
  • Agostino Lopizzo
    • Cardiology DepartmentUniversity of Foggia
  • Matteo Di Biase
    • Cardiology DepartmentUniversity of Foggia
    • Cardiology DepartmentUniversity of Foggia
Review

DOI: 10.1007/s00392-014-0718-y

Cite this article as:
Santoro, F., Tarantino, N., Pellegrino, P.L. et al. Clin Res Cardiol (2014) 103: 955. doi:10.1007/s00392-014-0718-y

Abstract

Radiotherapy (RT) is one of the main therapeutic options for malignancy treatment; nevertheless, RT is not free from side effects, including an increased risk for secondary neoplasms and other organs injury. Cardiovascular complications are the second most frequent fatal post-RT sequelae, which physicians should be aware of and ready to diagnose early and cure. This review therefore aims to examine epidemiology, pathogenesis and clinical dose-correlated manifestations of RT-induced cardiovascular disease. Future perspectives on screening, prevention and treatment are also provided.

Keywords

RadiotherapyCardiovascular complicationsIonizing radiationsCardiovascular diseaseCancer

Copyright information

© Springer-Verlag Berlin Heidelberg 2014