Cardiovascular sequelae of radiation therapy
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- Santoro, F., Tarantino, N., Pellegrino, P.L. et al. Clin Res Cardiol (2014) 103: 955. doi:10.1007/s00392-014-0718-y
Radiotherapy (RT) is one of the main therapeutic options for malignancy treatment; nevertheless, RT is not free from side effects, including an increased risk for secondary neoplasms and other organs injury. Cardiovascular complications are the second most frequent fatal post-RT sequelae, which physicians should be aware of and ready to diagnose early and cure. This review therefore aims to examine epidemiology, pathogenesis and clinical dose-correlated manifestations of RT-induced cardiovascular disease. Future perspectives on screening, prevention and treatment are also provided.