, Volume 97, Issue 6, pp 397-401
Date: 14 Jan 2008

Tako-tsubo-like cardiomyopathy and extra-adrenal pheochromocytoma: case report and literature review

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Sirs: Transient left ventricular apical ballooning, also known as Tako-tsubo cardiomyopathy, has been described as being related to cases of acute coronary syndrome with normal coronary arteries [2, 5, 20, 21].

Several cases have been reported in the literature and some case series and studies have been published, proposing various etiologies for this dysfunction [2, 3, 5, 21]. The presence of positive markers for myocardial necrosis and the frequent temporal association with emotional stress point to an adrenergic trigger, which possibly, in combination with other factors that remain to be clarified, would lead to its development [21]. The best known and more often studied pathological condition where there is an adrenergic overload, due to excess of circulating catecholamines, is pheochromocytoma [11]. Other cases have been described connecting pheochromocytoma and Tako-tsubo-like phenomenon but reports on extra-adrenal variant are extremely uncommon [4, 17].

We herein describe the cas