Clinical Research in Cardiology

, Volume 95, Issue 6, pp 344–348

Coronary vasospasm–induced acute diastolic dysfunction in a patient with Raynaud’s phenomenon

  • Carsten Tschöpe
  • Dirk Westermann
  • Paul Steendijk
  • Mario Kasner
  • Martin Rudwaleit
  • Peter L. Schwimmbeck
  • Wolfgang C. Poller
  • Heinz-Peter Schultheiss
CASE REPORT

DOI: 10.1007/s00392-006-0384-9

Cite this article as:
Tschöpe, C., Westermann, D., Steendijk, P. et al. Clin Res Cardiol (2006) 95: 344. doi:10.1007/s00392-006-0384-9
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Summary

We present the case of a patient with severe dyspnea and Raynaud’s phenomenon. We could clarify, using invasive techniques including left ventricular conductance catheterization and coronary ergonovine provocation, that isolated diastolic dysfunction induced by coronary vasospasm were responsible for the symptoms. Systolic function was not affected. Short–term infusions with the prostacyclin analogue iloprost, known to act as a disease–modifying agent in patients suffering from Raynaud’s phenomenon, led to an improvement of cardiac function. Thus, episodes of dyspnea in patients with Raynaud’s phenomenon might be also interpretated as a coronary ischemia equivalent, which may belong to a visceral form of Raynaud’s phenomenon and which are sensitive to iloprost infusions.

Key words

Diastolic dysfunction coronary vasospasm pressure volume loops Raynaud’s phenomenon 

Copyright information

© Steinkopff-Verlag 2006

Authors and Affiliations

  • Carsten Tschöpe
    • 1
  • Dirk Westermann
    • 1
  • Paul Steendijk
    • 3
  • Mario Kasner
    • 1
  • Martin Rudwaleit
    • 2
  • Peter L. Schwimmbeck
    • 1
  • Wolfgang C. Poller
    • 1
  • Heinz-Peter Schultheiss
    • 1
  1. 1.Charitè—University Medicine Berlin, Campus Benjamin FranklinDepartment of Cardiology and PneumologyBerlinGermany
  2. 2.Department of Gastroenterology and RheumatologyCharité—University Medicine Berlin, Campus Benjamin FranklinBerlinGermany
  3. 3.Department of CardiologyLeiden University Medical CenterThe Netherlands

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