Comparison of EORTC Quality of Life Core Questionnaire (EORTC-QLQ-C30) and Gastrointestinal Quality of Life Index (GIQLI) in patients undergoing elective colorectal cancer resection
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
EORTC-QLQ-C30 questionnaires and GIQLI questionnaires are used to evaluate post-operative quality of life (QoL). It was not clear whether results of both instruments are comparable. Therefore, the level of agreement between both QoL questionnaires was evaluated in patients undergoing elective colorectal cancer resection.
Pre-operatively, 7 and 30 days after surgery 116 patients answered the EORTC-QLQ-C-30 and the GIQLI questionnaires in random order. Individual questions with similar content from each questionnaire were compared. Data for global QoL, physical (PF), emotional (EF) and social function (SF) were linearly transformed to fit a scale from 0 to 100. Data from the two instruments were correlated and the level of agreement between them was calculated according to the method of Bland and Altman.
A total of 308 data sets [(pre-op. n=116; 7th pod n=101; 30th post-operative day (pod) n=91)] were evaluated. Both instruments detected a reversible reduction of QoL after surgery and gave inferior results for patients with conditions known to impair QoL. EORTC-QLQ-C30 was more sensitive than GIQLI. The correlation between the two questionnaires for global QoL, PF and EF was good (r=0.53–0.66, p<0.01), but no correlation for SF was detected (r=−0.44, p=0.44). Linearly transformed scores from the two instruments differed considerably from −13 (95%CI −51 to 24) points (QoL) to 10 (−38 to 58) points (PF).
Although EORTC-QLQ-C30 scores and GIQLI scores from patients undergoing elective colorectal cancer surgery did correlate well, the level of agreement between the two instruments was quite low. Perioperative QoL data from the two instruments cannot be compared with each other.
- Pemberton JH, Phillips SF, Ready RR, Zinsmeister AR, Beahrs OH (1989) Quality of life after Brooke ileostomy and ileal pouch-anal anastomosis. Ann Surg 209:620–626
- Padilla GV, Grant MM, Lipsett J, Anderson PR, Rhiner M, Bogen C (1992) Health quality of life and colorectal cancer. Cancer 70:1450–1456
- Weeks JC, Nelson H, Gelber S, Sargent D, Schroeder G (2002) Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial. J Am Med Assoc 287:321–328 CrossRef
- Koller M, Kussmann J, Lorenz W, Rothmund M (1994) Measuring quality of life in after-care of tumor surgery. Methods, problems and applications. Chirurg 65:333–339
- Feinstein AR, Josephy B, Wells CK (1986) Scientific and clinical problems in indexes of functional disability. Ann Intern Med 105:413–420
- Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Fiuliberti A, Flechtner H, Fleishman SB, de Haes JCJM, Kaasa S, Klee M, Osoba D, Razavi D, Rofe PB, Schraub S, Sneeuw K, Sullivan M, Takeda F (1993) The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85:365–372
- Eypasch E, Williams JI, Wood-Dauphinée S, Ure B, Schmülling C, Neugebauer E, Troidl H (1995) Gastrointestinal Quality of Life Index: development, validation and application of a new instrument. Br J Surg 82:216–222
- Milsom JW, Böhm B (1996) Laparoscopic colorectal surgery. Springer, Berlin Heidelberg New York
- Fayers P, Aaronson NK, Bjordal K, Sullivan-M (1995) EORTC QLQ-C30 scoring manual. EORTC Quality of Life Study Group, Brussels
- Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet i:307–310
- Sprangers MAG, Aaronson NK (1991) The current status of quality-of-life assessment in surgical investigations. Theor Surg 6:165
- Bergman B, Aaronson NK, Ahmedzai S, Kaasa S, Sullivan M (1994) The EORTC QLQ-LC13: a modular supplement to the EORTC Core Quality of Life Questionnaire (QLQ-C30) for use in lung cancer clinical trials. EORTC StudyGroup on Quality of Life. Eur J Cancer 30A:635–642 CrossRef
- Bjordal K, Ahlner-Elmqvist, Tollesson, Jensen A, Razavi, Maher E, Kaasa S (1994) Development of a European Organization for Research and Treatment of Cancer (EORTC) questionnaire module to be used in quality of life assessments in head and neck cancer patients. EORTC Quality of Life Study Group. Acta Oncol 33:879–885
- Comparison of EORTC Quality of Life Core Questionnaire (EORTC-QLQ-C30) and Gastrointestinal Quality of Life Index (GIQLI) in patients undergoing elective colorectal cancer resection
International Journal of Colorectal Disease
Volume 19, Issue 6 , pp 554-560
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- Colorectal resection
- Quality of life
- Industry Sectors