, Volume 15, Issue 1, pp 68-70

Ectomesenchymoma of the prostate: histological diagnostic criteria

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A 5-month-old infant with an ectomesenchymoma (EMCH) of the prostate is described. The tumour was composed of embryonal rhabdomyosarcoma (RMS) and ganglioneuroma. Eight months after presentation the patient died of recurrent tumour, which caused intestinal obstruction. The tumour was initially diagnosed as an embryonal RMS on trans-rectal needle biopsies. The diagnosis of an EMCH is difficult if not impossible to make on needle-biopsy specimens. We suggest that pathologists should always consider an EMCH when confronted with a RMS or neuroectodermal tumour, and the use of immunohistochemical stains is recommended in this situation.

Accepted: 26 May 1998