Pediatric Surgery International

, Volume 28, Issue 7, pp 737–740

A novel t(3;8)(p13;q21.1) translocation in a case of lipoblastoma

Authors

    • Section of Pediatric Surgery, Department of Surgery, K4/752 Clinical Science CenterUniversity of Wisconsin
  • Bradley Maxfield
    • Department of Pediatric RadiologyUniversity of Wisconsin
  • Kara Gill
    • Department of Pediatric RadiologyUniversity of Wisconsin
  • Neha J. Patel
    • Department of Pediatric Hematology and OncologyUniversity of Wisconsin
  • Ankush Gosain
    • Section of Pediatric Surgery, Department of Surgery, K4/752 Clinical Science CenterUniversity of Wisconsin
Case Report

DOI: 10.1007/s00383-012-3081-y

Cite this article as:
Brinkman, A.S., Maxfield, B., Gill, K. et al. Pediatr Surg Int (2012) 28: 737. doi:10.1007/s00383-012-3081-y

Abstract

Lipoblastoma is a rare benign neoplasm of embryonic white fatty tissue primarily found in the extremities of children <3 years old (Batanian et al., Cancer Genet Cytogenet 125(1):10–13, 2001; McVay MR et al., J Pediatr Surg 41(6):1067–1071, 2006; Kamal et al., J Pediatr Surg 46(7):E9–E12, 2011). Translocations affecting the 8q11–13 region are commonly reported with lipoblastoma and proper diagnosis requires cytogenetic analysis to distinguish it from malignant myxoid liposarcoma (Miller et al., J Pediatr Surg 32(12):1771–1772, 1997; Morerio et al., Pediatr Blood Cancer 52(1):132–134, 2009). We describe an additional case of lipoblastoma containing a new translocation t(3;8)(p13;q21.1), which has not previously been reported in a healthy asymptomatic child.

Keywords

LipoblastomaTranslocationChromosome 8PLAG1t(3;8)(p13;q21.1)

Copyright information

© Springer-Verlag 2012