Pediatric Surgery International

, Volume 26, Issue 11, pp 1071–1075

Prenatal diagnosis of cloacal malformations

  • Andrea Bischoff
  • Marc A. Levitt
  • Foong Yen Lim
  • Carolina Guimarães
  • Alberto Peña
Original Article

DOI: 10.1007/s00383-010-2685-3

Cite this article as:
Bischoff, A., Levitt, M.A., Lim, F.Y. et al. Pediatr Surg Int (2010) 26: 1071. doi:10.1007/s00383-010-2685-3

Abstract

Introduction

Prenatal diagnosis of anorectal malformations currently occurs in 0–15.9% of screened cases. In cloacas, these numbers are unknown. We speculate that some images from prenatal ultrasound studies may suggest the diagnosis of cloaca, but are not recognized because of a lack of suspicion for this diagnosis.

Methods

A retrospective review of the medical records of 489 patients born with cloaca was performed; 95 of them had prenatal ultrasound reports that represent the material analyzed for this study. A literature review was performed, finding 31 publications, with 68 cloaca patients detected by prenatal images. The abnormal findings of our patients were compared with those described in the literature to determine the most common abnormal prenatal images found in patients with cloaca.

Results

The 95 ultrasound reports found in our patients described 270 abnormalities, the most frequent were: abdominal/pelvic cystic/mass (39), hydronephrosis (36), oligohydramnios (23), distended bowel/bowel obstruction (19), ascites (15), 2 vessel cord (14), dilated bladder (14), dilated ureter (14), polyhydramnios (10), echogenic bowel (8), multicystic kidney (8), “ambiguous genitalia” (7), hydrops fetalis (7), hydrocolpos (4), absent kidney (3), abnormal spine (3), and anorectal atresia (3). In spite of these findings, the radiologists who interpreted the studies only suspected a cloaca in 6 cases (6%). The literature review showed 212 abnormalities in 68 demonstrated cloaca patients. The most frequent were: abdominal/pelvic cystic/mass (46), hydronephrosis (44), ascites (21), oligohydramnios (20), distended bowel (11), multicystic dysplastic kidney (7), ambiguous genitalia (6), non-visualization of the bladder (6), two-vessel cord (5), dilated bladder (5), intraabdominal calcification (4), polyhydramnios (4), enterolithiasis (4), hydrometrocolpos (3), and dilated ureter (3).

Conclusion

We conclude that it is possible to suspect the diagnosis of cloaca, prenatally, more frequently than what currently occurs, looking at the same images but with an increased index of suspicion for cystic abdominal masses and a combination of gastrointestinal and urological abnormalities.

Keywords

Prenatal diagnosisAnorectal malformationCloaca

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Andrea Bischoff
    • 1
  • Marc A. Levitt
    • 1
  • Foong Yen Lim
    • 2
  • Carolina Guimarães
    • 3
  • Alberto Peña
    • 1
  1. 1.Colorectal Center for Children, Division of Pediatric SurgeryCincinnati Children’s Hospital Medical CenterCincinnatiUSA
  2. 2.Fetal Care Center of Cincinnati, Division of Pediatric SurgeryCincinnati Children’s Hospital Medical CenterCincinnatiUSA
  3. 3.Department of RadiologyCincinnati Children’s Hospital Medical CenterCincinnatiUSA