Child's Nervous System

, Volume 14, Issue 11, pp 617–622

Management of recurrent pilocytic astrocytoma with leptomeningeal dissemination in childhood

Authors

  • M. Tamura
    • Department of Neurosurgery, Gunma University School of Medicine, 3-39-22 Showa-machi, Maebashi, 371 Japan Fax: +81-27-233-6300
  • A. Zama
    • Department of Neurosurgery, Gunma University School of Medicine, 3-39-22 Showa-machi, Maebashi, 371 Japan Fax: +81-27-233-6300
  • H. Kurihara
    • Department of Neurosurgery, Gunma University School of Medicine, 3-39-22 Showa-machi, Maebashi, 371 Japan Fax: +81-27-233-6300
  • H. Fujimaki
    • Department of Neurosurgery, Gunma University School of Medicine, 3-39-22 Showa-machi, Maebashi, 371 Japan Fax: +81-27-233-6300
  • H. Imai
    • Department of Neurosurgery, Gunma University School of Medicine, 3-39-22 Showa-machi, Maebashi, 371 Japan Fax: +81-27-233-6300
  • T. Kano
    • Department of Neurosurgery, Gunma University School of Medicine, 3-39-22 Showa-machi, Maebashi, 371 Japan Fax: +81-27-233-6300
  • F. Saitoh
    • Department of Neurosurgery, Gunma University School of Medicine, 3-39-22 Showa-machi, Maebashi, 371 Japan Fax: +81-27-233-6300
BRIEF COMMUNICATION

DOI: 10.1007/s003810050286

Cite this article as:
Tamura, M., Zama, A., Kurihara, H. et al. Child's Nerv Syst (1998) 14: 617. doi:10.1007/s003810050286

Abstract

Two cases of recurrent pilocytic astrocytoma with leptomeningeal dissemination (LMD) are described. A 6-year-old boy presented with a cerebellar tumor, which was subtotally removed. Tumor recurrence with LMD occurred 4 years later. Reoperation for tumor removal followed by craniospinal irradiation stabilized the LMD over 5 years. A 4-year-old girl presented with a chiasmatic-hypothalamic tumor. Partial removal of the tumor was followed by radiation therapy. Tumor regrowth with LMD occurred 4 years later and was managed by reoperation, chemotherapy and radiotherapy. Tumor recurrence with LMD can be stabilized by multimodal treatment without tumor progression.

Key words Pilocytic astrocytomaCerebellar tumorChiasmatic gliomaHypothalamic gliomaLeptomeningeal dissemination
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© Springer-Verlag Berlin Heidelberg 1998