Favorable outcome of giant cell glioblastoma in a child Report of an 11-year survival period
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- Klein, R., Mölenkamp, G., Sörensen, N. et al. Child's Nerv Syst (1998) 14: 288. doi:10.1007/s003810050228
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Giant cell glioblastomas are defined as glioblastomas with a marked predominance of bizarre, multinucleated giant cells. They represent about 5% of all glioblastomas and can occur at any site of the central nervous system, but the temporal and frontal lobes are the sites of predilection. Overall, giant cell glioblastomas show a prolonged survival period compared with common glioblastoma multiforme, and survival periods of 7 and 9 years have been reported in adults. Here we report on a child aged 11 years at diagnosis, who has so far survived for 11 years since operation and adjunctive radio- and chemotherapy.