Child's Nervous System

, Volume 13, Issue 10, pp 556–559

Congenital immature teratoma of the fetal brain

  • C. H. Rickert
  • S. Probst-Cousin
  • F. Louwen
  • B. Feldt
  • F. Gullotta
CASE REPORT

DOI: 10.1007/s003810050137

Cite this article as:
Rickert, C., Probst-Cousin, S., Louwen, F. et al. Child's Nerv Syst (1997) 13: 556. doi:10.1007/s003810050137

Abstract

Congenital intracranial tumors are very rare and only account for 0.5–1.5% of all childhood brain tumors. Even rarer are those with prenatal manifestation. The most common of these present at birth are teratomas, which show divergent differentiation with 90% of them containing tissues from all three germ layers. We report a rare case of an intrauterine congenital immature teratoma in a female fetus at 23 weeks of gestation, which was sonographically diagnosed in vivo by detection of the tumor and associated craniomegaly. Because of the poor prognosis, termination of the pregnancy was induced by Rivanol instillation. The cerebral tumor was confirmed at autopsy and was not associated with any other malformations. Histological and immunohistochemical features of this tumor are presented.

Key words FetusBrain tumorCongenitalTeratomaImmunohistochemistry

Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • C. H. Rickert
    • 1
  • S. Probst-Cousin
    • 1
  • F. Louwen
    • 2
  • B. Feldt
    • 3
  • F. Gullotta
    • 1
  1. 1.Institut für Neuropathologie, Westfälische Wilhelms-Universität, Domagkstrasse 19, D-48149 Münster, Germany Tel.: (49) 251-8 35 69 72 Fax: (49) 251-8 35 69 71DE
  2. 2.Zentrum für Frauenheilkunde, Westfälische Wilhelms-Universität, Albert-Schweitzer-Strasse 33, D-48149 Münster, GermanyDE
  3. 3.Gerhard-Domagk-Institut für Pathologie, Westfälische Wilhelms-Universität, Domagkstrasse 17, D-48149 Münster, GermanyDE