Original Paper

Child's Nervous System

, Volume 21, Issue 11, pp 986-990

First online:

Head circumference and chronic positive pressure ventilation in children: a pilot study

  • Virginia S. KharaschAffiliated withPediatric Pulmonary Rehabilitation, Franciscan Hospital for ChildrenDivision of Respiratory Disease, Children’s Hospital Boston, Harvard Medical School Email author 
  • , Ning Tat Hamilton HuiAffiliated withUnited Christian Hospital
  • , Helene M. DumasAffiliated withResearch Center for Children with Special Health Care Needs, Franciscan Hospital for Children
  • , Stephen M. HaleyAffiliated withResearch Center for Children with Special Health Care Needs, Franciscan Hospital for ChildrenHealth and Disability Research Institute, Boston University
  • , Linda SpechtAffiliated withMedical and Rehabilitative Services, Franciscan Hospital for Children
  • , Andrew A. ColinAffiliated withDivision of Respiratory Disease, Children’s Hospital Boston, Harvard Medical School

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Methods

We reviewed the cases of 11 children <12 years of age with complex medical conditions and respiratory failure requiring chronic positive pressure ventilation (CPPV). We conducted a within-group comparison of average head circumference (HC) percentiles with each child’s age-expected 50th percentile value and a between-groups comparison with children with no history of ventilation. We examined the relationship between HC, peak levels of positive inspiratory pressure (PIP), and length of time on CPPV.

Results

We found that children on CPPV had an average HC value at the 71st percentile, significantly greater (p=0.009) than the age-expected 50th percentile; that children on CPPV had a greater (p=0.003) average HC percentile compared with children with complex medical conditions not on CPPV; and that peak levels of PIP had a moderately strong correlation to HC (r=0.689, p=0.019).

Conclusion

We conclude that children on CPPV have larger than expected HC and HC appears related to the peak level of PIP. Research to further investigate the relationship between HC and CPPV in children appears to be warranted.

Keywords

Children Mechanical ventilation Positive pressure Cranium Macrocephaly