World Journal of Urology

, Volume 18, Issue 1, pp 56–61

Myoblast therapy for stress urinary incontinence and bladder dysfunction

  • Teruhiko Yokoyama
  • Johnny Huard
  • Michael B. Chancellor
Article

DOI: 10.1007/s003450050010

Cite this article as:
Yokoyama, T., Huard, J. & Chancellor, M. World J Urol (2000) 18: 56. doi:10.1007/s003450050010

Abstract

The field of tissue engineering and gene therapy has an exciting and promising future. During the past few years we have begun a comprehensive effort to investigate the use of myoblasts to improve and expand the treatment of stress urinary incontinence and bladder dysfunction. Moreover, we can expect the application of myoblast-mediated ex vivo gene transfer in the field of urology. In this paper we discuss the compositions of and methods involving the use of myogenic or muscle-derived cells for tissue engineering and cell-mediated gene therapy.

Key words MyoblastBladderUrethraUrodynamicsIncontinenceGene therapyTissue engineering

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • Teruhiko Yokoyama
    • 1
  • Johnny Huard
    • 2
  • Michael B. Chancellor
    • 1
  1. 1.Division of Urologic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USAUS
  2. 2.Department of Orthopedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USAUS
  3. 3.Suite 700, Kaufmann Building, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA e-mail: chancellormb@msx.upmc.edu, Tel.: +1-412-6924096, Fax: +1-412-6924101US