World Journal of Urology

, Volume 22, Issue 4, pp 281–284

Pain during transrectal ultrasonography guided prostate biopsy: a randomized prospective trial comparing periprostatic infiltration with lidocaine with the intrarectal instillation of lidocaine-prilocain cream

Authors

  • Ioannis Adamakis
    • 1st Department of UrologyAthens University Medical School
  • Dionisios Mitropoulos
    • 1st Department of UrologyAthens University Medical School
    • 1st Department of UrologyAthens University Medical School
  • Christos Alamanis
    • 1st Department of UrologyAthens University Medical School
  • Konstantinos Stravodimos
    • 1st Department of UrologyAthens University Medical School
  • Aris Giannopoulos
    • 1st Department of UrologyAthens University Medical School
Free Paper

DOI: 10.1007/s00345-003-0386-4

Cite this article as:
Adamakis, I., Mitropoulos, D., Haritopoulos, K. et al. World J Urol (2004) 22: 281. doi:10.1007/s00345-003-0386-4

Abstract

Prostate biopsy is usually performed without anesthesia. We evaluated the patient’s perception of pain/discomfort experienced during the procedure in terms of the type of anesthesia used: periprostatic infiltration with 2% lidocaine, or intrarectal instillation of lidocaine-prilocain cream. A total of 198 patients were divided into three groups: group 1 (control group, n=40) received sonographic gel intrarectally prior to biopsy, group 2 (n=75) were given intrarectal instillation of lidocaine-prilocain cream, and group 3 (n=80) received periprostatic anesthesia by injecting 10 ml of 2% lidocaine. Pain after each biopsy was assessed using an 11-point linear visual analog pain scale. The mean pain scores were 5.1 in group 1, 4.8 in group 2, and 2.5 in group 3, resulting in a significant difference between group 3 and both groups 1 and 2, but not between groups 1 and 2. The incidence of biopsy-related adverse events did not differ among groups. Transrectal ultrasonographic guided periprostatic anesthesia is superior to intarectal instillation of lidocaine-prilocain cream.

Keywords

BiopsyLocal anestheticPainProstateTRUS

Copyright information

© Springer-Verlag 2003