European Radiology

, Volume 23, Issue 5, pp 1429–1442

Partial splenic embolisation using n-butyl cyanoacrylate: intraprocedural evaluation by magnetic resonance imaging

Authors

    • Department of Diagnostic RadiologyTokai University School of Medicine
  • Chihiro Itou
    • Department of Diagnostic RadiologyTokai University School of Medicine
  • Rick Wray
    • Department of Diagnostic RadiologyTokai University School of Medicine
  • Kazunori Myojin
    • Department of Diagnostic RadiologyTokai University School of Medicine
  • Takeshi Hashimoto
    • Department of Diagnostic RadiologyTokai University School of Medicine
  • Yoshimi Nagata
    • Department of Diagnostic RadiologyTokai University School of Medicine
  • Hiroshi Yamamuro
    • Department of Diagnostic RadiologyTokai University School of Medicine
  • Tomoatsu Tsuji
    • Department of Diagnostic RadiologyTokai University School of Medicine
  • Tamaki Ichikawa
    • Department of Diagnostic RadiologyTokai University School of Medicine
  • Kouichi Shiraishi
    • Department of Gastroenterology and HepatologyTokai University School of Medicine
  • Tatehiro Kagawa
    • Department of Gastroenterology and HepatologyTokai University School of Medicine
  • Tetsuya Mine
    • Department of Gastroenterology and HepatologyTokai University School of Medicine
  • Norihito Watanabe
    • Department of Gastroenterology and HepatologyTokai University School of Medicine
  • Mitsunori Matsumae
    • Department of NeurosurgeryTokai University School of Medicine
  • Bertrand Janne d’Othée
    • Division of Vascular and Interventional Radiology, Department of Diagnostic Radiology and Nuclear MedicineUniversity of Maryland School of Medicine
Vascular-Interventional

DOI: 10.1007/s00330-012-2711-z

Cite this article as:
Koizumi, J., Itou, C., Wray, R. et al. Eur Radiol (2013) 23: 1429. doi:10.1007/s00330-012-2711-z

Abstract

Objectives

To evaluate the use of diffusion-weighted imaging (DWI) for estimating infarcted splenic volume during partial splenic embolisation (PSE) using n-butyl cyanoacrylate (NBCA).

Methods

Twenty consecutive patients (57.2 ± 11.7 years) with hypersplenism underwent PSE. Intrasplenic branches were embolised using NBCA via a 2.1-French microcatheter aiming at infarction of 50 to 80 % of total splenic volume. Immediately after PSE, signal intensities (SI) of embolised and non-embolised splenic parenchyma were measured on DWI. Semi-automated volumetry (SAV) on DWI was compared with conventional manual volumetry (MV) on contrast-enhanced CT 1 week after PSE. Platelet counts were recorded before and after PSE.

Results

The SI on DWI in the embolised parenchyma decreased significantly (P < 0.01) to 24.7 ± 8.1 % as compared to non-embolised parenchyma. SAV and MV showed a strong correlation (r = 0.913 before PSE, r = 0.935 after PSE, P < 0.01) and significant (P < 0.01) reduction of normal splenic volume was demonstrated on both SAV (71.9 ± 12.4 %) and MV (73.6 ± 9.3 %) after PSE. Based on the initial SAV, three patients (15 %) underwent additional branch embolisation to reach sufficient infarction volume. Platelet counts elevated significantly (522.8 ± 209.1 %, P < 0.01) by 2 weeks after PSE. No serious complication was observed.

Conclusion

Immediate SI changes on DWI after PSE allowed semi-automated splenic volumetry on site.

Key Points

Partial splenic embolisation (PSE) is an important interventional technique for hypersplenism

Diffusion-weighted MR reveals an immediate decrease in signal in the embolised parenchyma

Such signal reduction permits semi-automated splenic volumetry on site.

This allows precise quantification of the amount of parenchyma infarcted, avoiding additional PSE.

Keywords

Diffusion-weighted imageComputed tomographyVolumetryn-butyl cyanoacrylatePartial splenic embolisation

Copyright information

© European Society of Radiology 2012