European Radiology

, Volume 23, Issue 5, pp 1429–1442

Partial splenic embolisation using n-butyl cyanoacrylate: intraprocedural evaluation by magnetic resonance imaging

  • Jun Koizumi
  • Chihiro Itou
  • Rick Wray
  • Kazunori Myojin
  • Takeshi Hashimoto
  • Yoshimi Nagata
  • Hiroshi Yamamuro
  • Tomoatsu Tsuji
  • Tamaki Ichikawa
  • Kouichi Shiraishi
  • Tatehiro Kagawa
  • Tetsuya Mine
  • Norihito Watanabe
  • Mitsunori Matsumae
  • Bertrand Janne d’Othée
Vascular-Interventional

DOI: 10.1007/s00330-012-2711-z

Cite this article as:
Koizumi, J., Itou, C., Wray, R. et al. Eur Radiol (2013) 23: 1429. doi:10.1007/s00330-012-2711-z

Abstract

Objectives

To evaluate the use of diffusion-weighted imaging (DWI) for estimating infarcted splenic volume during partial splenic embolisation (PSE) using n-butyl cyanoacrylate (NBCA).

Methods

Twenty consecutive patients (57.2 ± 11.7 years) with hypersplenism underwent PSE. Intrasplenic branches were embolised using NBCA via a 2.1-French microcatheter aiming at infarction of 50 to 80 % of total splenic volume. Immediately after PSE, signal intensities (SI) of embolised and non-embolised splenic parenchyma were measured on DWI. Semi-automated volumetry (SAV) on DWI was compared with conventional manual volumetry (MV) on contrast-enhanced CT 1 week after PSE. Platelet counts were recorded before and after PSE.

Results

The SI on DWI in the embolised parenchyma decreased significantly (P < 0.01) to 24.7 ± 8.1 % as compared to non-embolised parenchyma. SAV and MV showed a strong correlation (r = 0.913 before PSE, r = 0.935 after PSE, P < 0.01) and significant (P < 0.01) reduction of normal splenic volume was demonstrated on both SAV (71.9 ± 12.4 %) and MV (73.6 ± 9.3 %) after PSE. Based on the initial SAV, three patients (15 %) underwent additional branch embolisation to reach sufficient infarction volume. Platelet counts elevated significantly (522.8 ± 209.1 %, P < 0.01) by 2 weeks after PSE. No serious complication was observed.

Conclusion

Immediate SI changes on DWI after PSE allowed semi-automated splenic volumetry on site.

Key Points

Partial splenic embolisation (PSE) is an important interventional technique for hypersplenism

Diffusion-weighted MR reveals an immediate decrease in signal in the embolised parenchyma

Such signal reduction permits semi-automated splenic volumetry on site.

This allows precise quantification of the amount of parenchyma infarcted, avoiding additional PSE.

Keywords

Diffusion-weighted imageComputed tomographyVolumetryn-butyl cyanoacrylatePartial splenic embolisation

Copyright information

© European Society of Radiology 2012

Authors and Affiliations

  • Jun Koizumi
    • 1
  • Chihiro Itou
    • 1
  • Rick Wray
    • 1
  • Kazunori Myojin
    • 1
  • Takeshi Hashimoto
    • 1
  • Yoshimi Nagata
    • 1
  • Hiroshi Yamamuro
    • 1
  • Tomoatsu Tsuji
    • 1
  • Tamaki Ichikawa
    • 1
  • Kouichi Shiraishi
    • 2
  • Tatehiro Kagawa
    • 2
  • Tetsuya Mine
    • 2
  • Norihito Watanabe
    • 2
  • Mitsunori Matsumae
    • 3
  • Bertrand Janne d’Othée
    • 4
  1. 1.Department of Diagnostic RadiologyTokai University School of MedicineIsehara CityJapan
  2. 2.Department of Gastroenterology and HepatologyTokai University School of MedicineIseharaJapan
  3. 3.Department of NeurosurgeryTokai University School of MedicineIseharaJapan
  4. 4.Division of Vascular and Interventional Radiology, Department of Diagnostic Radiology and Nuclear MedicineUniversity of Maryland School of MedicineBaltimoreUSA