European Radiology

, Volume 21, Issue 10, pp 2046–2055

Patient acceptability of CT colonography compared with double contrast barium enema: results from a multicentre randomised controlled trial of symptomatic patients

  • Christian von Wagner
  • Samuel Smith
  • Steve Halligan
  • Alex Ghanouni
  • Emily Power
  • Richard J. Lilford
  • Dion Morton
  • Edward Dadswell
  • Wendy Atkin
  • Jane Wardle
  • For the SIGGAR Investigators
Gastrointestinal

DOI: 10.1007/s00330-011-2154-y

Cite this article as:
von Wagner, C., Smith, S., Halligan, S. et al. Eur Radiol (2011) 21: 2046. doi:10.1007/s00330-011-2154-y

Abstract

Objectives

To determine patient acceptability of barium enema (BE) or CT colonography (CTC).

Methods

After ethical approval, 921 consenting patients with symptoms suggestive of colorectal cancer who had been randomly assigned and completed either BE (N = 606) or CTC (N = 315) received a questionnaire to assess experience of the clinical episode including bowel preparation, procedure and complications. Satisfaction, worry and physical discomfort were assessed using an adapted version of a validated acceptability scale. Non-parametric methods assessed differences between the randomised tests and the effect of patient characteristics.

Results

Patients undergoing BE were significantly less satisfied (median 61, interquartile range [IQR] 54–67 vs. median 64, IQR 56–69; p = 0.003) and experienced more physical discomfort (median 40, IQR 29–52 vs. median 35.5, IQR 25–47; p < 0.001) than those undergoing CTC. Post-test, BE patients were significantly more likely to experience ‘abdominal pain/cramps’ (68% vs. 57%; p = 0.007), ‘soreness’ (57% vs. 37%; p < 0.001), ‘nausea/vomiting’ (16% vs. 8%; p = 0.009), ‘soiling’ (31% vs. 23%; p = 0.034) and ‘wind’ (92% vs. 84%; p = 0.001) and in the case of ‘wind’ to also rate it as severe (27% vs. 15%; p < 0.001).

Conclusion

CTC is associated with significant improvements in patient experience. These data support the case for CTC to replace BE.

Keywords

CTColonographyVirtual colonoscopyBarium enemaColonCancerPatient preference

Copyright information

© European Society of Radiology 2011

Authors and Affiliations

  • Christian von Wagner
    • 1
  • Samuel Smith
    • 1
  • Steve Halligan
    • 2
    • 6
  • Alex Ghanouni
    • 1
  • Emily Power
    • 1
  • Richard J. Lilford
    • 3
  • Dion Morton
    • 4
  • Edward Dadswell
    • 5
  • Wendy Atkin
    • 5
  • Jane Wardle
    • 1
  • For the SIGGAR Investigators
  1. 1.Department of Epidemiology and Public HealthUniversity College LondonLondonUK
  2. 2.Centre for Medical ImagingUniversity College LondonLondonUK
  3. 3.Department of EpidemiologyBirmingham UniversityBirminghamUK
  4. 4.Department of SurgeryBirmingham UniversityBirminghamUK
  5. 5.Department of Surgery and CancerImperial College LondonLondonUK
  6. 6.Centre for Medical ImagingUniversity College HospitalLondonUK