European Radiology

, Volume 20, Issue 9, pp 2257–2264

Liver virtual non-enhanced CT with dual-source, dual-energy CT: a preliminary study

  • Long-Jiang Zhang
  • Jin Peng
  • Sheng-Yong Wu
  • Z. Jane Wang
  • Xin-Sheng Wu
  • Chang-Sheng Zhou
  • Xue-Man Ji
  • Guang-Ming Lu
Hepatobiliary-Pancreas

DOI: 10.1007/s00330-010-1778-7

Cite this article as:
Zhang, L., Peng, J., Wu, S. et al. Eur Radiol (2010) 20: 2257. doi:10.1007/s00330-010-1778-7

Abstract

Purpose

To compare virtual non-enhanced liver CT (VNCT) from dual-energy CT (DECT) with true non-enhanced liver CT (TNCT) in patients.

Methods

A total of 102 patients underwent multi-phase abdominal CT. Liver arterial VNCT (VNCTA) and portovenous VNCT (VNCTV) images were derived from the arterial and portovenous DECT data. The mean CT number, signal to noise ratio (SNR), image quality, contrast to noise (CNR) of liver lesions, lesion detectability and radiation dose were compared.

Results

There was no difference in mean CT numbers of all organs (all P > 0.05). SNR on VNCT images was higher than that of TNCT (all P < 0.001). Image quality of VNCT was diagnostic but lower than that of TNCT (P < 0.001). VNCTA images were superior to VNCTV (P < 0.001). VNCTA and VNCTV detected 78 (91%) and 70 (81%) of 86 hepatic focal lesions visualised on TNCT. There was no difference in the size, attenuation and CNR of focal hepatic lesions (all P > 0.05), but SNR of the lesions on VNCT was higher than that on TNCT (P < 0.001). Radiation dose of biphase DECT was lower than that of routine triphase CT (P < 0.001).

Conclusion

VNCTA may potentially replace TNCT as part of a multi-phase liver imaging protocol with consequent saving in radiation dose.

Keywords

Dual-energy CTVirtual non-enhanced CTLiverPanoramic 3D

Abbreviations

VNCT

virtual non-enhanced CT

VNCTA

virtual non-enhanced CT images derived from the arterial phase dual-energy CT data

VNCTV

virtual non-enhanced CT images derived from the portovenous phase dual-energy CT data

TNCT

true non-enhanced liver CT

Copyright information

© European Society of Radiology 2010

Authors and Affiliations

  • Long-Jiang Zhang
    • 1
  • Jin Peng
    • 2
  • Sheng-Yong Wu
    • 3
  • Z. Jane Wang
    • 4
  • Xin-Sheng Wu
    • 1
  • Chang-Sheng Zhou
    • 1
  • Xue-Man Ji
    • 1
  • Guang-Ming Lu
    • 1
  1. 1.Department of Medical Imaging, Jinling Hospital, Clinical School of Medical CollegeNanjing UniversityNanjingChina
  2. 2.Department of Radiology, Bailu HospitalXiamenChina
  3. 3.Medical Imaging Institute of TianjinTianjinChina
  4. 4.Section of Abdominal Imaging, Department of Radiology and Biomedical ImagingUniversity of CaliforniaSan FranciscoUSA