European Radiology

, 18:2485

First online:

CT colonography and cost-effectiveness

  • Ifigeneia MavranezouliAffiliated withNational Collaborating Centre for Mental Health, Centre for Outcomes Research and Effectiveness, Sub-department of Clinical Health Psychology, University College London
  • , James E. EastAffiliated withWolfson Unit for Endoscopy, St Marks Hospital, Imperial College London
  • , Stuart A. TaylorAffiliated withSpecialist X-Ray, University College HospitalDepartment of Imaging, University College Hospital Email author 

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CT colonography (CTC) is increasingly advocated as an effective initial screening tool for colorectal cancer. Nowadays, policy-makers are increasingly interested in cost-effectiveness issues. A number of studies assessing the cost-effectiveness of CTC have been published to date. The majority of findings indicate that CTC is probably not cost-effective when colonoscopy is available, but this conclusion is sensitive to a number of key parameters. This review discusses the findings of these studies, and considers those factors which most influence final conclusions, notably intervention costs, compliance rates, effectiveness of colonoscopy, and the assumed prevalence and natural history of diminutive advanced polyps.


Colonography Computed tomography Colon polyps Colonoscopy Economics