European Radiology

, 18:2363

Diagnostic performance of detecting breast cancer on computed radiographic (CR) mammograms: comparison of hard copy film, 3-megapixel liquid-crystal-display (LCD) monitor and 5-megapixel LCD monitor

Authors

    • Department of Diagnostic RadiologyTohoku University, Graduate School of Medicine
  • Akihiko Suzuki
    • Department of Surgical OncologyTohoku University, Graduate School of Medicine
  • Nachiko Uchiyama
    • National Cancer Center, Research Center for Cancer Prevention and Screening
  • Noriaki Ohuchi
    • Department of Surgical OncologyTohoku University, Graduate School of Medicine
  • Shoki Takahashi
    • Department of Diagnostic RadiologyTohoku University, Graduate School of Medicine
Breast

DOI: 10.1007/s00330-008-1016-8

Cite this article as:
Yamada, T., Suzuki, A., Uchiyama, N. et al. Eur Radiol (2008) 18: 2363. doi:10.1007/s00330-008-1016-8

Abstract

The purpose was to compare observer performance in the detection of breast cancer using hard-copy film, and 3-megapixel (3-MP) and 5-megapixel (5-MP) liquid crystal display (LCD) monitors in a simulated screening setting. We amassed 100 sample sets, including 32 patients with surgically proven breast cancer (masses present, N = 12; microcalcifications, N = 10; other types, N = 10) and 68 normal controls. All the mammograms were obtained using computed radiography (CR; sampling pitch of 50 μm). Twelve mammographers independently assessed CR mammograms presented in random order for hard-copy and soft-copy reading at minimal 4-week intervals. Observers rated the images on seven-point (1 to 7) and continuous (0 to 100) malignancy scales. Receiver-operating-characteristics analysis was performed, and the average area under the curve (AUC) was calculated for each modality. The jackknife method with the Bonferroni correction was applied to multireader/multicase analysis. The average AUC values for the 3-MP LCD, 5-MP LCD, and hard-copy film were 0.954, 0.947, and 0.956 on the seven-point scale and 0.943, 0.923, and 0.944 on the continuous scale, respectively. There were no significant differences among the three modalities on either scale. Soft-copy reading using 3-MP and 5-MP LCDs is comparable to hard-copy reading for detecting breast cancer.

Keywords

Breast neoplasmDigital radiographyData displayLiquid crystalsROC curve

Abbreviations

3MP

3-megapixel

5MP

5-megapixel

LCD

liquid crystal display

AUC

area under the curve

DMIST

Digital Mammographic Imaging Screening Trial

CR

computed radiography

BI-RADS

Breast Imaging Reporting and Data System

DICOM

Digital Imaging and Communications in Medicine

GSDF

greyscale standard display function

ROC

receiver-operating characteristic

FFDM

full-field digital mammography

Copyright information

© European Society of Radiology 2008