European Radiology

, Volume 18, Issue 2, pp 376–383

Value of contrast-enhanced ultrasonography for detecting renal infarcts proven by contrast enhanced CT. A feasibility study

Authors

    • UCO di RadiologiaUniversità di Trieste, Ospedale di Cattinara
  • Alberto Martegani
    • Servizio di Diagnostica per ImmaginiOspedale Valduce
  • Luca Aiani
    • Servizio di Diagnostica per ImmaginiOspedale Valduce
  • Roberta Zappetti
    • UCO di RadiologiaUniversità di Trieste, Ospedale di Cattinara
  • Stefano Cernic
    • UCO di RadiologiaUniversità di Trieste, Ospedale di Cattinara
  • Maria Assunta Cova
    • UCO di RadiologiaUniversità di Trieste, Ospedale di Cattinara
Urogenital

DOI: 10.1007/s00330-007-0747-2

Cite this article as:
Bertolotto, M., Martegani, A., Aiani, L. et al. Eur Radiol (2008) 18: 376. doi:10.1007/s00330-007-0747-2

Abstract

The effectiveness of contrast-enhanced ultrasonography (CEUS) in the evaluation of patients with acute renal infarcts was investigated, using contrast-enhanced helical computed tomography (CT) as the reference imaging procedure. Twenty-seven consecutive patients with acute renal infarcts detected with contrast-enhanced helical CT underwent CEUS. Digital cine-clips of CEUS were evaluated by two independent readers blinded to CT findings. Image quality was rated subjectively on a four-point scale. Then, readers were asked to assign a confidence level in diagnosis of renal infarct at the upper pole, medium portion, and lower pole of each kidney according to a five-degree scale, ranging from definitely absent to definitely present. ROC curve analysis was employed to assess the overall confidence of diagnosis of infarct, and weighted kappa values were calculated to assess inter-reader agreement. The subjective image quality of CEUS was lower than the image quality of CT at the upper poles. However, the diagnostic performance of CEUS was excellent (area under receiver-operator characteristic curve 0.992 ± 0.006 for reader 1; 0.991 ± 0.007 for reader 2), with very good inter-reader agreement (weighted kappa value = 0.83). CEUS is a reproducible tool to detect acute renal infarcts in men, with a diagnostic performance approaching that of CT.

Keywords

Microbubble contrast agents Ultrasound Kidney Renal infarction Contrast-enhanced ultrasonography

Copyright information

© Springer-Verlag 2007