European Radiology

, Volume 17, Issue 8, pp 1979–1984

Accuracy of automated volumetry of pulmonary nodules across different multislice CT scanners

Authors

    • Department of Diagnostic RadiologyRWTH Aachen University
  • Julia Ley-Zaporozhan
    • Department of RadiologyGerman Cancer Research Center
  • H. A. Gietema
    • Department of Diagnostic RadiologyUniversity Hospital Utrecht
  • Andre Czech
    • Department of Diagnostic RadiologyMarienhospital Düsseldorf
  • Georg Mühlenbruch
    • Department of Diagnostic RadiologyRWTH Aachen University
  • Andreas H. Mahnken
    • Department of Diagnostic RadiologyRWTH Aachen University
  • Markus Katoh
    • Department of Diagnostic RadiologyRWTH Aachen University
  • Annemarie Bakai
    • CT DivisionSiemens Medical Solutions
  • Marcos Salganicoff
    • CAD ApplicationsSiemens Medical Solutions
  • Stefan Diederich
    • Department of Diagnostic RadiologyMarienhospital Düsseldorf
  • Mathias Prokop
    • Department of Diagnostic RadiologyUniversity Hospital Utrecht
  • Hans-Ulrich Kauczor
    • Department of RadiologyGerman Cancer Research Center
  • Rolf W. Günther
    • Department of Diagnostic RadiologyRWTH Aachen University
  • Joachim E. Wildberger
    • Department of Diagnostic RadiologyRWTH Aachen University
Experimental

DOI: 10.1007/s00330-006-0562-1

Cite this article as:
Das, M., Ley-Zaporozhan, J., Gietema, H.A. et al. Eur Radiol (2007) 17: 1979. doi:10.1007/s00330-006-0562-1

Abstract

The purpose of this study was to compare the accuracy of an automated volumetry software for phantom pulmonary nodules across various 16-slice multislice spiral CT (MSCT) scanners from different vendors. A lung phantom containing five different nodule categories (intraparenchymal, around a vessel, vessel attached, pleural, and attached to the pleura), with each category comprised of 7–9 nodules (total, n = 40) of varying sizes (diameter 3–10 mm; volume 6.62 mm3–525 mm3), was scanned with four different 16-slice MSCT scanners (Siemens, GE, Philips, Toshiba). Routine and low-dose chest protocols with thin and thick collimations were applied. The data from all scanners were used for further analysis using a dedicated prototype volumetry software. Absolute percentage volume errors (APE) were calculated and compared. The mean APE for all nodules was 8.4% (±7.7%) for data acquired with the 16-slice Siemens scanner, 14.3% (±11.1%) for the GE scanner, 9.7% (±9.6%) for the Philips scanner and 7.5% (±7.2%) for the Toshiba scanner, respectively. The lowest APEs were found within the diameter size range of 5–10 mm and volumes >66 mm3. Nodule volumetry is accurate with a reasonable volume error in data from different scanner vendors. This may have an important impact for intraindividual follow-up studies.

Keywords

Multislice CTPulmonary noduleNodule volumetryAutomated volumetryChest CT

Copyright information

© Springer-Verlag 2007