, Volume 17, Issue 8, pp 1979-1984
Date: 06 Jan 2007

Accuracy of automated volumetry of pulmonary nodules across different multislice CT scanners

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Abstract

The purpose of this study was to compare the accuracy of an automated volumetry software for phantom pulmonary nodules across various 16-slice multislice spiral CT (MSCT) scanners from different vendors. A lung phantom containing five different nodule categories (intraparenchymal, around a vessel, vessel attached, pleural, and attached to the pleura), with each category comprised of 7–9 nodules (total, n = 40) of varying sizes (diameter 3–10 mm; volume 6.62 mm3–525 mm3), was scanned with four different 16-slice MSCT scanners (Siemens, GE, Philips, Toshiba). Routine and low-dose chest protocols with thin and thick collimations were applied. The data from all scanners were used for further analysis using a dedicated prototype volumetry software. Absolute percentage volume errors (APE) were calculated and compared. The mean APE for all nodules was 8.4% (±7.7%) for data acquired with the 16-slice Siemens scanner, 14.3% (±11.1%) for the GE scanner, 9.7% (±9.6%) for the Philips scanner and 7.5% (±7.2%) for the Toshiba scanner, respectively. The lowest APEs were found within the diameter size range of 5–10 mm and volumes >66 mm3. Nodule volumetry is accurate with a reasonable volume error in data from different scanner vendors. This may have an important impact for intraindividual follow-up studies.