European Radiology

, Volume 17, Issue 8, pp 1979–1984

Accuracy of automated volumetry of pulmonary nodules across different multislice CT scanners

  • Marco Das
  • Julia Ley-Zaporozhan
  • H. A. Gietema
  • Andre Czech
  • Georg Mühlenbruch
  • Andreas H. Mahnken
  • Markus Katoh
  • Annemarie Bakai
  • Marcos Salganicoff
  • Stefan Diederich
  • Mathias Prokop
  • Hans-Ulrich Kauczor
  • Rolf W. Günther
  • Joachim E. Wildberger
Experimental

DOI: 10.1007/s00330-006-0562-1

Cite this article as:
Das, M., Ley-Zaporozhan, J., Gietema, H.A. et al. Eur Radiol (2007) 17: 1979. doi:10.1007/s00330-006-0562-1
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Abstract

The purpose of this study was to compare the accuracy of an automated volumetry software for phantom pulmonary nodules across various 16-slice multislice spiral CT (MSCT) scanners from different vendors. A lung phantom containing five different nodule categories (intraparenchymal, around a vessel, vessel attached, pleural, and attached to the pleura), with each category comprised of 7–9 nodules (total, n = 40) of varying sizes (diameter 3–10 mm; volume 6.62 mm3–525 mm3), was scanned with four different 16-slice MSCT scanners (Siemens, GE, Philips, Toshiba). Routine and low-dose chest protocols with thin and thick collimations were applied. The data from all scanners were used for further analysis using a dedicated prototype volumetry software. Absolute percentage volume errors (APE) were calculated and compared. The mean APE for all nodules was 8.4% (±7.7%) for data acquired with the 16-slice Siemens scanner, 14.3% (±11.1%) for the GE scanner, 9.7% (±9.6%) for the Philips scanner and 7.5% (±7.2%) for the Toshiba scanner, respectively. The lowest APEs were found within the diameter size range of 5–10 mm and volumes >66 mm3. Nodule volumetry is accurate with a reasonable volume error in data from different scanner vendors. This may have an important impact for intraindividual follow-up studies.

Keywords

Multislice CTPulmonary noduleNodule volumetryAutomated volumetryChest CT

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Marco Das
    • 1
  • Julia Ley-Zaporozhan
    • 2
  • H. A. Gietema
    • 3
  • Andre Czech
    • 4
  • Georg Mühlenbruch
    • 1
  • Andreas H. Mahnken
    • 1
  • Markus Katoh
    • 1
  • Annemarie Bakai
    • 5
  • Marcos Salganicoff
    • 6
  • Stefan Diederich
    • 4
  • Mathias Prokop
    • 3
  • Hans-Ulrich Kauczor
    • 2
  • Rolf W. Günther
    • 1
  • Joachim E. Wildberger
    • 1
  1. 1.Department of Diagnostic RadiologyRWTH Aachen UniversityAachenGermany
  2. 2.Department of RadiologyGerman Cancer Research CenterHeidelbergGermany
  3. 3.Department of Diagnostic RadiologyUniversity Hospital UtrechtUtrechtThe Netherlands
  4. 4.Department of Diagnostic RadiologyMarienhospital DüsseldorfDüsseldorfGermany
  5. 5.CT DivisionSiemens Medical SolutionsForchheimGermany
  6. 6.CAD ApplicationsSiemens Medical SolutionsMalvernUSA