European Radiology

, Volume 17, Issue 6, pp 1452–1463

Evaluation of in-stent restenosis in proximal coronary arteries with multidetector computed tomography (MDCT)


    • Department of RadiologyCHU Rangueil
  • D. Carrie
    • Department of CardiologyCHU Rangueil
  • M. Bennaceur
    • Department of RadiologyCHU Rangueil
  • E. Maupas
    • Department of CardiologyCHU Rangueil
  • V. Lauwers
    • Department of EpidemiologyCHU Rangueil
  • M. Mhem
    • Department of CardiologyCHU Rangueil
  • T. Lhermusier
    • Department of CardiologyCHU Rangueil
  • M. Elbaz
    • Department of CardiologyCHU Rangueil
  • F. Joffre
    • Department of RadiologyCHU Rangueil
  • H. Rousseau
    • Department of RadiologyCHU Rangueil
  • J. Puel
    • Department of CardiologyCHU Rangueil

DOI: 10.1007/s00330-006-0510-0

Cite this article as:
Chabbert, V., Carrie, D., Bennaceur, M. et al. Eur Radiol (2007) 17: 1452. doi:10.1007/s00330-006-0510-0


The purpose of this study was to assess the ability of 16-slice computed tomography (CT) to detect in-stent restenosis of proximal coronary arteries. From November 2002 to April 2004, 134 consecutive patients with proximal stents (3.25 ± 0.47 mm) were prospectively studied. Multidetector CT (MDCT) was performed 24 h (baseline) and 6 months after angioplasty and analysed by two radiologists blinded to the results of the coronary angiography. Sensitivity, specificity, positive and negative predictive values for in-stent restenosis were compared with conventional quantitative coronary angiography (QCA). Stenosis with a diameter ≥50% was considered diagnostic of in-stent restenosis. The CT analysis was performed in 131 and 114 patients at baseline and 6 months, respectively. The in-stent lumen was evaluable in 111 (121 stents) and 99 patients (108 stents) at baseline and 6 months, respectively. The prevalence of in-stent restenosis was 22.5%. Restenoses were correctly identified in 91.7 and 87.5% by the two radiologists. The sensitivity, specificity, positive and negative predictive values for the assessment of significant in-stent restenosis were 92, 67, 43, 97% and 87, 66, 41, 95% for the radiologists, respectively. MDCT is a potential non-invasive technique for the screening of in-stent restenosis of proximal coronary arteries that needs further improvements.


Multidetector computed tomographyCoronary stentsCoronary angiography

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© Springer-Verlag 2006