Rheumatology International

, Volume 17, Issue 2, pp 61–66

Esophageal manometry in systemic sclerosis: screening procedure or confined to symptomatic patients?

  • G. Lock
  • M. Zeuner
  • R. H. Straub
  • R. Hein
  • B. Lang
  • J. Schölmerich
  • A. Holstege
ORIGINAL ARTICLEORIGINAL ARTICLE

DOI: 10.1007/s002960050010

Cite this article as:
Lock, G., Zeuner, M., Straub, R. et al. Rheumatology International (1997) 17: 61. doi:10.1007/s002960050010

Abstract

The predictive value of esophagus-related symptoms for the diagnosis of esophageal dysmotility induced by systemic sclerosis (SSc) was prospectively evaluated in 50 consecutive patients with SSc. Patients were classified as symptomatic when either dysphagia or repeated episodes of heartburn were present. All patients underwent esophageal manometry; SSc-induced esophageal dysfunction was diagnosed when there was aperistalsis or marked hypocontractility of the distal two-thirds of the esophageal body. Twenty-nine patients (58%) had a history of esophagus-related symptoms, while 21 patients (42%) were asymptomatic. Compared to esophageal manometry, esophagus-related symptoms had a sensitivity of 64%, a specificity of 52%, a negative predictive value of 50% and a positive predictive value of 62% for the diagnosis of SSc-induced esophageal dysfunction. In conclusion, the association of esophagus-related symptoms and esophageal motility pattern is poor. As clinical management strategies depend on proof of esophageal dysfunction, screening examinations are mandatory in all patients with SSc.

Key words Systemic sclerosisEsophagusManometryDysphagiaHeartburn

Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • G. Lock
    • 1
  • M. Zeuner
    • 1
  • R. H. Straub
    • 1
  • R. Hein
    • 2
  • B. Lang
    • 1
  • J. Schölmerich
    • 1
  • A. Holstege
    • 1
  1. 1.University of Regensburg, Department of Internal Medicine I, University Hospital, D-93042 Regensburg, Germany Tel.: 0049/941 944 7014; Fax: 0049/941 944 7016DE
  2. 2.Department of Dermatology, University Hospital, D-93042 Regensburg, GermanyDE