Rheumatology International

, Volume 33, Issue 10, pp 2671–2673

Does vasculitis alone cause AVN? A review of literature

Short Communication

DOI: 10.1007/s00296-012-2467-4

Cite this article as:
Abraham, R.R. & Meyerhoff, J.O. Rheumatol Int (2013) 33: 2671. doi:10.1007/s00296-012-2467-4


AVN is caused by a disease, or severe trauma that affects the blood supply to the bone or in many cases may be idiopathic, with no known cause. AVN pathophysiology is most closely linked to SLE literature, and there is a strong cause and effect relationship between corticosteroid intake and AVN development in SLE patients, and AVN is extremely rare in the absence of steroid use. Apart from few anecdotal reports, there is no data on exact pathophysiologic mechanisms responsible for AVN in the setting of vasculitis. We saw a 69-year-old man with femoral AVN and a possibility of vasculitis as the underlying cause was raised by the radiologist, and hence we present this literature search on vasculitis per se causing AVN of the bone.


Avascular necrosisSteroidsSLEOsteonecrosis

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  1. 1.Department of Medicine, Sinai Hospital Program in Internal MedicineJohns Hopkins UniversityBaltimoreUSA
  2. 2.University of Arkansas for Medical SciencesLittle RockUSA
  3. 3.Division of RheumatologySinai Hospital of BaltimoreBaltimoreUSA
  4. 4.Johns Hopkins University School of MedicineBaltimoreUSA