Review

Rheumatology International

, Volume 32, Issue 5, pp 1121-1133

First online:

Evidence-based, interdisciplinary guidelines for anti-inflammatory treatment of uveitis associated with juvenile idiopathic arthritis

  • A. HeiligenhausAffiliated withDepartment of Ophthalmology, St. Franziskus HospitalGerman Ophthalmological Society, Augenabteilung, Uveitiszentrum, St. Franziskus Hospital Email author 
  • , H. MichelsAffiliated withSociety for Childhood and Adolescent Rheumatology, Deutsches Zentrum für Kinder- und Jugendrheumatologie
  • , C. SchumacherAffiliated withDepartment of Ophthalmology, St. Franziskus HospitalGerman Ophthalmological Society, Augenabteilung, Uveitiszentrum, St. Franziskus Hospital
  • , I. KoppAffiliated withWorking group of the Scientific Medical Specialty Societies
  • , U. NeudorfAffiliated withSociety for Childhood and Adolescent Rheumatology, Universitäts Kinderklinik
  • , T. NiehuesAffiliated withSociety for Childhood and Adolescent Rheumatology, HELIOS Klinikum Krefeld, Zentrum für Kinder- und Jugendmedizin
  • , H. BausAffiliated withParents’ Association for Children with Uveitis and Their Families
  • , M. BeckerAffiliated withGerman Ophthalmological Society, Stadtspital Triemli, Augenklinik
  • , B. BertramAffiliated withProfessional Association of Ophthalmologists, Augenarztpraxis
    • , G. DanneckerAffiliated withSociety for Childhood and Adolescent Rheumatology, Olgahospital, Klinik für Kinder- und Jugendmedizin, Pädiatrie
    • , C. DeuterAffiliated withGerman Ophthalmological Society, Universitäts-Augenklinik
    • , I. FoeldvariAffiliated withSociety for Childhood and Adolescent Rheumatology, Hamburger Zentrum für Kinder- und Jugendrheumatologie, Klinikum Eilbeck
    • , M. FroschAffiliated withSociety for Childhood and Adolescent Rheumatology, Universitätskinderklinik Münster, Klinik und Poliklinik für Kinder- und Jugendmedizin
    • , G. GanserAffiliated withSociety for Childhood and Adolescent Rheumatology, St.-Josefs-Stift, Sendenhorst, Kinder- und Jugendrheumatologie
    • , M. GaubitzAffiliated withGerman Society for Rheumatology, Akademie für Manuelle Therapie
    • , G. GerdesAffiliated withParents’ Association for Children with Uveitis and Their Families
    • , G. HorneffAffiliated withSociety for Childhood and Adolescent Rheumatology, Asklepios Klinik St. Augustin, Zentrum für Kinder- und Jugendmedizin
    • , A. IllhardtAffiliated withPsychologischer Dienst, St. Josef-Stift, Sendenhorst, Kinder- und Jugendrheumatologie
    • , F. MackensenAffiliated withGerman Ophthalmological Society, Universitäts-Augenklinik
    • , K. MindenAffiliated withSociety for Childhood and Adolescent Rheumatology, Deutsches Rheumaforschungszentrum
    • , U. PleyerAffiliated withGerman Ophthalmological Society, Universitätsaugenklinik, Charite
    • , M. SchneiderAffiliated withGerman Society for Rheumatology, Heinrich-Heine-Universität, Klinik, und Poliklinik für Rheumatologie
    • , N. WagnerAffiliated withSociety for Childhood and Adolescent Rheumatology, Rheinisch-Westfälische Technische Hochschule, Kinder- und Jugendmedizin
    • , M. ZierhutAffiliated withGerman Ophthalmological Society, Universitäts-Augenklinik

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Uveitis in juvenile idiopathic arthritis (JIA) is frequently associated with the development of complications and visual loss. Topical corticosteroids are the first-choice therapy, and immunosuppression is commonly used. However, treatment has not been standardized. Representatives from the German Ophthalmological Society, Society for Childhood and Adolescent Rheumatology, and the German Society for Rheumatology reached consensus on a standardized treatment strategy according to disease severity in the individual patient. The recommendations were based on a systematic literature analysis in MEDLINE and consensus expert meetings. Evidence and recommendations were graded, and an algorithm for anti-inflammatory treatment and final statements confirmed in a Delphi method. An interdisciplinary, evidence-based treatment guideline for JIA uveitis is presented.

Keywords

Adolescence Children Consensus Evidence-based medicine Juvenile idiopathic arthritis Rheumatic diseases Therapy Uveitis