Rheumatology International

, Volume 32, Issue 4, pp 1091–1094

Extremely high serum ferritin levels as a main diagnostic tool of adult-onset Still’s disease

  • Srdan Novak
  • Felina Anic
  • Tea Schnurrerer Luke-Vrbanić
Short Communication

DOI: 10.1007/s00296-011-1834-x

Cite this article as:
Novak, S., Anic, F. & Luke-Vrbanić, T.S. Rheumatol Int (2012) 32: 1091. doi:10.1007/s00296-011-1834-x

Abstract

Adult-onset Still’s disease is a rare systemic inflammatory disease of unknown aetiology characterised by typical symptoms including daily high spiking fever, evanescent salmon-pink rash, sore throat, arthritis/arthralgias and polyserositis. The laboratory findings usually show neutrophilic leucocytosis, seronegativity and raised serum transaminases. We describe six typical cases. All of them had serum ferritin above 5,000 µg/L. Although there are few theories about the origin of the high ferritin level, an extremely high serum ferritin above 5,000 µg/L should be the main diagnostic tool of adult-onset Still’s disease.

Keywords

Adult-onset Still’s diseaseDiagnosisHyperferritinaemiaLaboratory findings

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Srdan Novak
    • 1
  • Felina Anic
    • 1
  • Tea Schnurrerer Luke-Vrbanić
    • 2
  1. 1.Rheumatology and Clinical Immunology Department, Internal MedicineUniversity Hospital (CHC) RijekaRijekaCroatia
  2. 2.Physical Medicine and Rehabilitation DepartmentUniversity Hospital (CHC) RijekaRijekaCroatia