Rheumatology International

, Volume 32, Issue 2, pp 303–306

Investigation of the veins in patients with Behçet’s disease with no known vascular event by Doppler ultrasonography

  • Bunyamin Kisacik
  • Cem Oren
  • Timucin Kasifoglu
  • Sedat Yilmaz
  • Omer Yilmaz
  • Ismail Simsek
  • Hakan Erdem
  • Salih Pay
  • Mutlu Saglam
  • Ayhan Dinc
Original Article

DOI: 10.1007/s00296-010-1603-2

Cite this article as:
Kisacik, B., Oren, C., Kasifoglu, T. et al. Rheumatol Int (2012) 32: 303. doi:10.1007/s00296-010-1603-2

Abstract

In Behçet’s disease, deep venous thrombosis occurs primarily in the lower extremities. Total recanalization rate is low, so thrombotic segment could be detected by imaging afterward. For disclosing vein involvement, leg swelling is commonly queried in the history taking in those patients. However, there are no data about the presence of “silent” thrombosis in patients with BD. We aimed at investigating the integrity of venous vessels in BD, without any known vascular event by using Doppler ultrasonography (DU). Patients having past events revealed in the vascular questionnaire or physical findings attributable to vascular disease were excluded. Various degree of venous insufficiency was detected in 74 patients in BD (74%), 24 out of 33 patients (72%) in AS and in 8 out of 34 (25%) in HC group. All were at the lower extremities, and there is no difference in the frequency between BD and AS, while both were significantly higher than in HC (P = 0.001, and 0.004, respectively). Six patients with BD (6%) have chronic venous thrombi at the lower extremities and none in either AS and HC. As a non-invasive method, DU of lower extremities may disclose “silent” thrombosis. Venous insufficiency in those patients should be considered cautiously as an indicator of vein involvement.

Keywords

Behçet’s disease Deep-vein thrombosis Doppler ultrasonography 

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Bunyamin Kisacik
    • 1
  • Cem Oren
    • 2
  • Timucin Kasifoglu
    • 1
  • Sedat Yilmaz
    • 1
  • Omer Yilmaz
    • 2
  • Ismail Simsek
    • 1
  • Hakan Erdem
    • 1
  • Salih Pay
    • 1
  • Mutlu Saglam
    • 2
  • Ayhan Dinc
    • 1
    • 3
  1. 1.Division of Rheumatology, Department of Internal MedicineGulhane School of MedicineAnkaraTurkey
  2. 2.Department of RadiologyGulhane School of MedicineAnkaraTurkey
  3. 3.GATA, Romatoloji Bilim Dalı, EtlikAnkaraTurkey

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