Rheumatology International

, Volume 32, Issue 1, pp 249–251

Etanercept and anakinra can prolong febrile episodes in patients with hyperimmunoglobulin D and periodic fever syndrome

  • Hiba M. Shendi
  • Deirdre Walsh
  • J. David M. Edgar
Case Report

DOI: 10.1007/s00296-009-1322-8

Cite this article as:
Shendi, H.M., Walsh, D. & Edgar, J.D.M. Rheumatol Int (2012) 32: 249. doi:10.1007/s00296-009-1322-8

Abstract

Hyperimmunoglobulin D and periodic fever syndrome (HIDS) is a rare, hereditary autoinflammatory condition, characterized by recurrent inflammatory episodes. There is no proven treatment for HIDS, but various drugs including, non-steroidal anti-inflammatory drugs, colchicine, steroids, statins and thalidomide have all been tried. Recently, some patients have demonstrated a good clinical response to either etanercept or anakinra. We report a case of a 10-year-old girl who experienced prolonged and severe inflammatory attacks, when she was treated with etanercept, and later with anakinra.

Keywords

Hyper IgD and periodic fever syndrome (HIDS)EtanerceptAnakinraTreatmentAdverse effects

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Hiba M. Shendi
    • 1
  • Deirdre Walsh
    • 1
    • 2
  • J. David M. Edgar
    • 1
  1. 1.Royal Victoria HospitalBelfastNorthern Ireland, UK
  2. 2.Causeway HospitalColeraineNorthern Ireland, UK