Rheumatology International

, Volume 32, Issue 1, pp 249–251

Etanercept and anakinra can prolong febrile episodes in patients with hyperimmunoglobulin D and periodic fever syndrome

  • Hiba M. Shendi
  • Deirdre Walsh
  • J. David M. Edgar
Case Report

DOI: 10.1007/s00296-009-1322-8

Cite this article as:
Shendi, H.M., Walsh, D. & Edgar, J.D.M. Rheumatol Int (2012) 32: 249. doi:10.1007/s00296-009-1322-8

Abstract

Hyperimmunoglobulin D and periodic fever syndrome (HIDS) is a rare, hereditary autoinflammatory condition, characterized by recurrent inflammatory episodes. There is no proven treatment for HIDS, but various drugs including, non-steroidal anti-inflammatory drugs, colchicine, steroids, statins and thalidomide have all been tried. Recently, some patients have demonstrated a good clinical response to either etanercept or anakinra. We report a case of a 10-year-old girl who experienced prolonged and severe inflammatory attacks, when she was treated with etanercept, and later with anakinra.

Keywords

Hyper IgD and periodic fever syndrome (HIDS) Etanercept Anakinra Treatment Adverse effects 

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Hiba M. Shendi
    • 1
  • Deirdre Walsh
    • 1
    • 2
  • J. David M. Edgar
    • 1
  1. 1.Royal Victoria HospitalBelfastNorthern Ireland, UK
  2. 2.Causeway HospitalColeraineNorthern Ireland, UK

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