Rheumatology International

, Volume 28, Issue 2, pp 171–174

Antiphospholipid syndrome: a predisposing factor for early onset HELLP syndrome

  • Panagiotis Tsirigotis
  • George Mantzios
  • Vassiliki Pappa
  • Konstantinos Girkas
  • George Salamalekis
  • Angellos Koutras
  • Vassiliki Giannopoulou
  • Konstantina Spirou
  • Alexia Balanika
  • Sotirios Papageorgiou
  • Anthi Travlou
  • John  Dervenoulas
Case Report

DOI: 10.1007/s00296-007-0386-6

Cite this article as:
Tsirigotis, P., Mantzios, G., Pappa, V. et al. Rheumatol Int (2007) 28: 171. doi:10.1007/s00296-007-0386-6

Abstract

Hemolysis elevated liver enzymes low platelets syndrome (HELLP) is a relatively rare pregnancy-related thrombotic microangiopathic disorder, usually observed during the third trimester. Its incidence seems to be increased in patients with antiphospholipid syndrome (APS). In this report, we describe a 33-year-old pregnant woman with previously known primary APS who developed early onset HELLP syndrome during the 15th week of gestation. We also review the literature about this interesting relationship between APS and HELLP.

Keywords

Antiphospholipid syndrome (APS)HELLP syndrome–hepatic infarctions

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Panagiotis Tsirigotis
    • 1
  • George Mantzios
    • 2
  • Vassiliki Pappa
    • 1
  • Konstantinos Girkas
    • 1
  • George Salamalekis
    • 3
  • Angellos Koutras
    • 3
  • Vassiliki Giannopoulou
    • 1
  • Konstantina Spirou
    • 4
  • Alexia Balanika
    • 4
  • Sotirios Papageorgiou
    • 1
  • Anthi Travlou
    • 2
  • John  Dervenoulas
    • 1
  1. 1.2nd Department of Internal Medicine, PropaudeuticUniversity of Athens, “ATTIKON” General University HospitalAthensGreece
  2. 2.Department of Transfusion ServiceUniversity of Athens, “ATTIKON” General University HospitalAthensGreece
  3. 3.Third Department of Obstetrics and GynecologyUniversity of Athens, “ATTIKON” General University HospitalAthensGreece
  4. 4.2nd Department of Radiology University of Athens, “ATTIKON” General University HospitalAthensGreece