Rheumatology International

, Volume 26, Issue 8, pp 758–759

Deep venous thrombosis in a patient with Behçet’s disease and homozygous prothrombin (factor II) G20210A mutation on oral contraceptive pills

Case report

DOI: 10.1007/s00296-005-0048-5

Cite this article as:
Uthman, I., Otrock, Z. & Taher, A. Rheumatol Int (2006) 26: 758. doi:10.1007/s00296-005-0048-5


Behçet’s disease (BD) is a multisystemic disease of unknown aetiology characterized by chronic relapsing oral aphthous lesions, genital ulcers, uveitis, and vasculopathy of both arteries and veins of all sizes. We present the case of a female patient, with BD on oral contraceptive pills, who sustained deep venous thrombosis of the long saphenous vein. The patient was found to be a carrier of a homozygous mutation of the prothrombin (factor II) G20210A gene. Our case suggests that a thrombophilia work-up may be warranted in BD patients, especially young women before they are prescribed oral contraceptives.


Behcet’s disesaseVasculopathyProthrombin

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  1. 1.Department of Internal Medicine, Faculty of MedicineAmerican University of Beirut Medical CenterBeirutLebanon