, Volume 25, Issue 5, pp 398-400
Date: 10 Dec 2004

Familial Mediterranean fever protracted febrile myalgia in children: report of two cases

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Familial Mediterranean fever (FMF) is characterised by recurring, acute, self-limiting episodes of fever accompanied by serosal, synovial or cutaneous inflammation [1, 2]. One of the most common complications of FMF results from the deposition of amyloid A [3]. The clinical picture of FMF has been expanded appreciably in the last 10 years when additional features have been described, including severe myalgia [4], the protracted febrile myalgia syndrome [5], scrotal swelling [6] and cardiac involvement [7]. In this letter, we described protracted febrile myalgia with FMF in two children and draw attention to the protracted febrile myalgia as an entity that requires corticosteroid treatment.

Case 1

An 11-year-old girl was admitted to the paediatrics clinics with fever and severe myalgia in lower extremities lasting for 15 days. Due to the myalgia, she was unable to walk without help. She was the second child of a consanguineous marriage, and she had three healthy siblings. Her mother had a ...