Acute erythroleukemia in a rheumatoid arthritis patient during low-dose methotrexate therapy
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- Choi, BR., Ahn, MJ., Lee, W.S. et al. Rheumatol Int (2005) 25: 311. doi:10.1007/s00296-004-0502-9
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Acute leukemia is uncommonly seen with rheumatoid arthritis during or following treatment with low-dose methotrexate, a safe and effective treatment for the arthritic condition. We describe here a 68-year-old woman with rheumatoid arthritis who developed acute erythroleukemia during low-dose methotrexate therapy (total dose 1702.5 mg). This may be the first such case reported in the literature.