Rheumatology International

, Volume 25, Issue 5, pp 345–349

Auditory event-related brain potentials in fibromyalgia syndrome

  • Ece Alanoğlu
  • Umit Hıdır Ulaş
  • Fatih Özdağ
  • Zeki Odabaşı
  • Aytül Çakçı
  • Okay Vural
Original article

DOI: 10.1007/s00296-004-0443-3

Cite this article as:
Alanoğlu, E., Ulaş, U.H., Özdağ, F. et al. Rheumatol Int (2005) 25: 345. doi:10.1007/s00296-004-0443-3

Abstract

Objective

The aim of this study was to investigate cognitive functions using auditory event-related brain potentials (ERP) in fibromyalgia syndrome (FMS).

Methods

The P300 component of ERP was studied in 36 female FMS patients and 22 control subjects. The short form 36 (SF-36) medical outcome study was used to determine quality of life. Number of tender points and disease duration were noted. Cognitive functions were evaluated with P300.

Results

The symptoms were discrepant in FMS (P<0.001). The scores of the eight SF-36 subgroups in FMS patients were significantly lower than in the control group (P<0.001). Fibromyalgia syndrome patients had prolonged latency and reduced amplitude of P300 (P<0.001). No correlation was found between the subgroups of SF-36, tender point count, disease duration, and P300.

Conclusion

The results of our study reveal that FMS affects quality of life and dysfunction in cognitive abilities can be determined by brain event-related potentials.

Keywords

Cognitive dysfunction Brain event-related potentials Fibromyalgia P300 Short form 36 

Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • Ece Alanoğlu
    • 1
    • 3
  • Umit Hıdır Ulaş
    • 2
  • Fatih Özdağ
    • 2
  • Zeki Odabaşı
    • 2
  • Aytül Çakçı
    • 1
  • Okay Vural
    • 2
  1. 1.Physical Therapy and Rehabilitation DepartmentSocial Security Hospital of AnkaraAnkaraTurkey
  2. 2.Gülhane School of MedicineDepartment of NeurologyAnkaraTurkey
  3. 3.Oyak 4.AnkaraTurkey

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